Ping Xu, Ph.D.

Professor

Phone: (804) 827-6264

Fax: (804) 828-0150

          
           
             
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    Selected Publications

  1. Ge X, Shi X, Shi L, Liu J, Stone V, Kong F, Kitten T, Xu P*. Involvement of NADH Oxidase in Biofilm Formation in Streptococcus sanguinis. PLoS One. 2016 Mar 7;11(3):e0151142. doi: 10.1371/journal.pone.0151142. eCollection 2016 PMID: 26950587(PDF).

  2. Ge X, Yu Y, Zhang M, Chen L, Chen W, Elrami F, Kong F, Kitten T, Xu P*. Involvement of NADH Oxidase in Competition and Endocarditis Virulence in Streptococcus sanguinis. Infect Immun. 2016 Feb 29. pii: IAI.01203-15. PMID: 26930704 (PDF)

  3. Stone VN, Parikh HI, El-Rami F, Ge X, Chen W, Zhang Y, Kellogg GE, Xu P*. Identification of Small-Molecule Inhibitors against Meso-2, 6-Diaminopimelate Dehydrogenase from Porphyromonas gingivalis. PLoS One. 2015 Nov 6;10(11):e0141126. doi: 10.1371/journal.pone.0141126. eCollection 2015 PMID: 26544875(PDF)

  4. Crump KE, Bainbridge B, Brusko S, Turner LS, Ge X, Stone V, Xu P, Kitten T*. The Relationship of the Lipoprotein SsaB, Manganese, and Superoxide Dismutase in Streptococcus sanguinis Virulence for Endocarditis. Mol Microbiol. 2014 Jun;92(6):1243-59. doi: 10.1111/mmi.12625. PMID: 24750294 (PDF)

  5. Xu P*, Gunsolley J. Application of metagenomics in understanding oral health and disease. Virulence. 2014 Mar 18;5(3). Review. PMID: 24642489 (PDF)

  6. Rhodes DV, Crump KE, Makhlynets O, Snyder M, Ge X, Xu P, Stubbe J, Kitten T*. Genetic Characterization and Role in Virulence of the Ribonucleotide Reductases of Streptococcus sanguinis. J Biol Chem. 2014 Feb 28;289(9):6273-87. doi: 10.1074/jbc.M113.533620. Epub 2013 Dec 31. PMID: 24381171 (PDF)

  7. Evans K, Stone V, Chen L, Ge X, Xu P*. Systematic Study Of Gene Functions For Chain Length In Streptococcus sanguinis. Microbiology. 2014 Feb;160(Pt2):307-15.doi: 10.1099/mic.0.071688-0. PMID: 24295823 (PDF)

  8. Ge X, Rodriguez R, Trinh M, Gunsolley J, Xu P.* Oral microbiome of deep and shallow dental pockets in chronic periodontitis. PLoS One. 2013 Jun 6;8(6):e65520. doi: 10.1371/journal.pone.0065520.(article)

  9. Trihn M, Ge X, Dobson A, Kitten T, Munro CL, Xu P*. Two-Component System Response Regulators Involved in Virulence of Streptococcus pneumoniae TIGR4 in Infective Endocarditis. PLoS One. 2013;8(1):e54320. doi: 10.1371/journal.pone.0054320. (article)

  10. Chen L, Ge X, Wang X, Patel JR, Xu P*. SpxA1 Involved in Hydrogen Peroxide Production, Stress Tolerance and Endocarditis Virulence in Streptococcus sanguinis. PLoS One. 2012;7(6):e40034. Epub 2012 Jun 29.(article)

  11. Xu P*, Ge X, Chen L, Wang X, Dou Y, Xu JZ, Patel JR, Stone V, Trinh M, Evans K, Kitten T, Bonchev D, Buck GA. (2011) Genome-wide essential gene identification in Streptococcus sanguinis. Scientific Reports Volume: 1, Article number: 125 DOI: doi:10.1038/srep00125. (article)

  12. Manque PA, Probst C, Pereira MC, Rampazzo RC, Ozaki LS, Pavoni DP, Silva Neto DT, Carvalho MR, Xu P, Serrano MG, Alves JM, Meirelles Mde N, Goldenberg S, Krieger MA, Buck GA*. (2011) Trypanosoma cruzi infection induces a global host cell response in cardiomyocytes. Infect Immun. 2011 May;79(5):1855-62. Epub 2011 Feb 22. (PDF)

  13. Chen L, Ge X, Dou Y, Wang X, Patel JR, Xu P*.(2010) Identification of hydrogen peroxide production related genes in Streptococcus sanguinis and their functional relationship with pyruvate oxidase. Microbiology. 2010 Sep 16. (PDF)

  14. Ge X, Kitten T, Munro CL, Conrad DH, Xu P* (2010) Pooled Protein Immunization for Identification of Cell Surface Antigens in Streptococcus sanguinis. PLoS ONE 5(7): e11666. doi:10.1371/journal.pone.0011666 (PDF)

  15. Das S, Kanamoto T, Ge X, Xu P, Unoki T, Munro CL, Kitten T*. Contribution of lipoproteins and lipoprotein processing to endocarditis virulence in Streptococcus sanguinis. J Bacteriol. 2009 Jul;191(13):4166-79. (PDF).

  16. Ge X, Kitten T, Chen Z, Lee S, Munro CL and Xu P*. Identification of Streptococcus sanguinis genes required for biofilm formation and examination of their role in endocarditis virulence. Infection & Immunity, June; 76 (6), 2008. (PDF).

  17. Xu P, Alves JM, Kitten T, Brown A, Chen Z, Ozaki LS, Manque P, Ge X, Serrano MG, Puiu D, Hendricks S, Wang Y, Chaplin MD, Akan D, Paik S, Peterson DL, Macrina FL, Buck GA*. Genome of the opportunistic pathogen Streptococcus sanguinis. J Bacteriol. 2007 Apr;189(8):3166-75. (PDF).

  18. Xu P, Widmer G, Wang Y, Ozaki LS, Alves JM, Serrano MG, Puiu D, Manque P, Akiyoshi D, Mackey AJ, Pearson WR, Dear PH, Bankier AT, Peterson DL, Abrahamsen MS, Kapur V, Tzipori S, Buck GA*. The genome of Cryptosporidium hominis. Nature. 2004 Oct 28;431(7012):1107-12. (PDF)

  19. Abrahamsen MS*, Templeton TJ, Enomoto S, Abrahante JE, Zhu G, Lancto CA, Deng M, Liu C, Widmer G, Tzipori S, Buck GA, Xu P, Bankier AT, Dear PH, Konfortov BA, Spriggs HF, Iyer L, Anantharaman V, Aravind L, Kapur V. Complete genome sequence of the apicomplexan, Cryptosporidium parvum. Science. 2004 Apr 16;304(5669):441-5 (PDF)