BNFO 301 
Introduction to Bioinformatics
Items for each day generally indicate what is to be done before class
Spring 2011 

January February March April May

Monday
 
Wednesday
   
    2: Genome Sequencing
    Notes -
Overview of genome sequencing
    Notes - Where sequences come from
    Article: Myers et al. (2000) + Tour
    Questionnaire
    Please e-mail responses to any part of
           Problem Set 1 by end of Friday
   
7: Genome Sequencing
    Article: Myers et al. (2000) + Tour
            (especially SQ14 of the tour)
    Questionnaire
    Lab: Sequence Assembly example
            Problem Set 2: Molec Biol Investigations (by request)
            Problem Set 3: Genome sequencing
  9: Intro to Molecular Biology
    Notes:
Gene regulation and phage
    Questionnaire
     Please e-mail responses to any part of
            Problem Set 2 by end of Friday
   
14: Intro to Molecular Biology
      Article: Madsen et al. (1999) + Tour
      Discussion: Problem Set 3 (Genome sequencing)
      Questionnaire
      Lab: Problem Set 3 (Genome sequencing)
  16: General problem session
      Questionnaire - What questions to discuss?
      Special Review Session: 10:00AM-? BNFO Computer Lab
      Special Review Session: 4:30-6:00PM BNFO Computer Lab
      Exam 1 distributed < 6:15 PM
               What to expect
               Ground rules
               Part I due Friday, Feb 16, 5:30 PM
   
21: Exam 1 due 8:30 AM
      Post-exam questionnaire
      Genome Analysis (no reading for today)
      Post-mortem: Exam 1
      Lab: Intro to BioBIKE
               Notes: Introduction to mapping
               Notes: Elements of a loop
               Problem Set 4: Practice with loops and mapping
  23: Genome Analysis
      Notes: Search for FMRP in Drosophila
      Notes: Introduction to mapping
      Notes: Elements of a loop
      Post-mortem: Exam 1 (continued)
      Questionnaire
      Please e-mail responses to any part of
            Problem Set 4 by end of Friday
  *
28: Genome Analysis
      Article - Hatfull et al (2008) review + tour (Part I and Part II)
      Questionnaire
      Lab: Intro to BioBIKE and Statistics
              Problem Set 5 - Blast and Dotplot
      OR  Tour - Was Mendel Right? (Part I and Part II)
              Problem Set 6 - Statistics
       
* David Harper, Chief Scientific Officer and founder of BioControl will speak at 10:00 AM, Friday, February 25, Harris Hall Rm 2122, on phage therapy.
   You can read here about BioControl's approach and Sulakvelidze et al (2001) for a general account of phage therapy.