BNFO 300 
Molecular Biology Through Discovery
Path to class (Tuesday, Sep 3) - Protein (Sanger)
(please press SUBMIT button when finished)
Fall 2019  


My advice on the matters for the day (as listed in the calendar):

Protein
  • Sanger and Tuppy (1951): Main topic for today, the first three sections of the companion to the article -- understanding the experimental procedure.
     
  • Paper chromatography: A direct assault on the experimental procedure. This tutorial is possibly your best shot at understanding the experiment. I suggest you go through it before class and offer questions, if you have any. Shouldn't take long.
     
  • What is a Gene?: Last chance to work on this in class. I suggest that you go as far as you can before class, so that if you encounter a problem, we can solve it.
     
  • Problem Set 2: Protein: We will spend time on any question(s) you like. Default is Problem Set 2 #1. You can let this go until class, or not.

I. Basic Information

  1. Your name 
II. Old business (no need to repeat anything you've said in a previous questionnaire)
  1. Protein
    Anything further you'd like to discuss regarding the notes entitled Protein?

     
  2. What is a Gene?
    Any obstacles that have come up in your progress through What is a Gene?

     
  3. Research Proposal
    Are you relatively clear on the nature of the research proposal and how it will play out? (if not, try the Research Proposal page)
    Are you happy with progress in identifying a mentor?
III. Sanger & Tuppy (1951)
  1. Have you found and downloaded the article Sanger & Tuppy (1951) cited in the companion?
    Are you sure you got the right one? How do you know?

     
  2. How far have you gotten in a productive reading of the article (not just the companion)?
    You can answer by referring to the last section you read or the last study question you addressed (e.g. SQ12) in the companion.

     
  3. Consider how comfortable you are with the following topics (as defined by the companion to Sanger and Tuppy):
    • The distinction between a research article and a review article? Between a research article and a science news article?
    • The overall strategy Sanger & Tuppy used to determine the sequence of insulin
    • What paper chromatography is and how it works (did the presentation on paper chromatography help you?)
    • Study questions 1 through 9

    With this in mind, how could class time best be spent to meet your needs?
    As always, refer to specific matters and relate your current understanding and efforts you've made to address your discomfort.
    Do you have any other questions concerning the material in the notes?

IV. Miscellaneous

A. Are group problem sessions in class useful to you? Can you think of any way in which they could be more useful?

B. Any other comments, questions, suggestions, or concerns you may have?

Thanks!

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