BNFO 300 
Molecular Biology Through Discovery
Schedule for Advisory Panels on Research Proposals
Tuesday, Dec 9, through Friday, Dec 12
Fall 2017 

  1. Guidance for Presenters
  2. Guidance for Panelists
  3. Schedule of Panels

A. Guidance for Presenters (see How to Prepare for a Panel for further advice)

  • Where and When: See Schedule
    Presenters should be in the room at least 5 minutes before the time of their panel. Non-presenters (and panelists) are welcome at any time.
     
  • Duration of presentation: Up to seven minutes and no more. At six minutes, you'll hear a courteous tinkle of a bell. At seven minutes, a bone-shaking clang will stop your presentation if it has not already concluded. If you're in the middle of a sentence, you'll be permitted to complete the sentence (with no more than one conjunction), but that's it.
     
  • Duration of question and answer period: Up to eight minutes, marked by a bell. Questions will be posed by the panel concerning the presentation and the written proposal.
     
  • Loading presentations: There won't be time to download your presentation. It must be on the computer before the panels begin. This can be done in either of two ways:
     
    • E-mail your presentation to me by 15 minutes before the beginning of the panel
    • Bring your presentation on a memory device by 15 minutes before the beginning of the panel

    Do not expect to download it from your e-mail or upload it on the spot from your memory device.
     

B. Guidance for Panelists

  • Reviewers: Each proposal has been assigned a primary reviewer and a secondary reviewer, noted in the schedule. The primary reviewer will begin the discussion after the presentation. All panelists are invited, nay, urged to join in as well.
     
  • Goals of the proposal: Please see How to Write a Research Proposal to see the goals presenters were asked to address. If you like, you can also take a look at an example of a proposal.
     
  • Goals of the presentation: Please see How to Give a Presentation Focused on an Experiment to see the goals presenters were asked to address.
     
  • Goals of the course: In brief, the primary goal of the course was to bring students into the scientific process of approximating truth, giving due weight to what has been observed, limited by how it was observed, and distinguishing observation from mere assertion. In not brief, see the Course Objectives.
     
  • Goals of the review process:

    • Please consider whether the proposal and presentation have addressed the general goals of the course. For example, a generally useful question would be "How do you know that [some assertion] is true?".
       
    • Please consider whether the proposal and presentation have addressed the specific goals of presentations and proposals. For example, if the proposal and presentation does not make abundantly clear that the presenter understands the principle behind the proposed experiment, you might through probing questions give the presenter an opportunity to display (or perhaps discover) such understanding. Do not presume that just because the term "Western blot" rolls confidently off the tongue that the presenter has any idea what it is.
       
    • Presenters are to understand at least one experiment thoroughly, but in doing so, they may not have learned a lot about other experiments. Don't fault them for not having a Plan B.
       
  • Feedback: The eight minutes of questioning will by itself provide valuable feedback to the presenter. You're certainly invited to provide written feedback as well if you can, but feel no guilt if you can't. Presenters have until Sunday, May 14, to revise their proposals, if they wish.
     
  • Thanks: Please accept them for the bracing experience you've given fledgling molecular biologists.

C. Schedule of Panels

Titles link to the written proposals.
Presentation links to the corresponding powerpoint presentation (active the day of the presentation).

Panel I: Wednesday, Dec 13, 2:00 - 3:00 PM. Harris Hall Room 3112 (see map)
Panelists: Gregorio Gil, Glen Kellogg, Jitender Mehla, Sarah Rothschild

Cove SoyarsRole of hydrophobicity in Ser-83 amino acid substitutions of DNA gyrase subunit A encoding gyrA
Primary: Glen Kellogg, Secondary: Gregorio Gil       (Presentation)
Rebecca CulpepperDiscovery of possible connection between cln3 and cisd2 gene through notch signaling
Primary: Sarah Rothschild, Secondary: Jitender Mehla       (Presentation)
Mouni TalariThe upregulation of ceramide synthase 3 via PGJ2, INT131, and S26948 in psoriatic human epidermal keratinocytes and normal human epidermal keratinocytes
Primary: Gregorio Gil, Secondary: Sarah Rothschild       (Presentation)
Sam PortilloComparison of phenylalanine v. tyrosine rotamers with respect to alpha helix structure using 3D modeling software
Primary: Jitender Mehla, Secondary: Glen Kellogg       (Presentation)

Panel II: Thursday, Dec 14, 9:00 - 10:00 AM. Harris Hall Room 3142 (see map)
Panelists: Luni Emdad, Eun Lee, Andrew van der Vaart

Oluchi ChigbuDo levels of EPA in C. elegans alter transcriptional regulation of NPR-1?
Primary: Andrew van der Vaart, Secondary: Luni Emdad       (Presentation)
Mailat YonasIs p53 more likely to trigger apoptosis or cellular senescence as a response to a tumor or DNA damage?
Primary: Luni Emdad, Secondary: Eun Lee       (Presentation)
Angela MichalakHow does CagA in H. pylori contribute to apoptosis in gastric cancer cells?
Primary: Eun Lee, Secondary: Luni Emdad       (Presentation)
Samhitha DhandamudyExamining the role of verapamil on protein kinase C activity in diabetic mice hepatic cells
Primary: Andrew van der Vaart, Secondary: Eun Lee       (Presentation)

Panel III: Thursday, Dec 14, 10:00 - 11:00 AM. Harris Hall Room 3142 (see map)
Panelists: Jill Bettinger, Becca Martin, Binks Wattenberg

Shradda Adhikari Genetically modifications on ERAP2 and its effect on lymphocyte activation
Primary: Becca Martin, Secondary: Jill Bettinger       (Presentation)
Sharoon Arshad Furin deletion in B cells alters ADAM10 prodomain processing and the downstream effects on allergic asthma
Primary: Binks Wattenberg, Secondary: Jill Bettinger       (Presentation)
Akhil Ramaswamy5-HT1B-receptor regulation by p-GSK3B due to acute ethanol exposure on mice
Primary: Jill Bettinger, Secondary: Binks Wattenberg       (Presentation)
Ashley AroraMeasurement of natural killer cells and T-cells in ERAP2-N and ERAP2-K
Primary: Becca Martin, Secondary: Binks Wattenberg       (Presentation)

Panel IV: Thursday, Dec 14, 11:00 - 12:15 AM. Harris Hall Room 3142 (see map)
Panelists: John Bigbee, Javier Gonzales-Maeso, Derek Prosser, Greg Walsh

Shahzeb HasanThe role of G-beta-gamma in adenylyl cyclase super activation following chronic morphine exposure
Primary: Derek Prosser, Secondary: Javier Gonzales-Maeso       (Presentation)
Amanda AtrashDisruption of NDEL1 via knockdown of DISC1 stunts dendritic spine structure in the hippocampus region of mice
Primary: John Bigbee, Secondary: Greg Walsh       (Presentation)
Aarthi PrakashIdentifying the conserved residues of LapA that are required for protein-protein interactions
Primary: Javier Gonzales-Maeso, Secondary: Greg Walsh       (Presentation)
Shwetha KochiInhibition of prion-like properties in alpha-synuclein using promazine derivatives
Primary: Derek Prosser, Secondary: John Bigbee       (Presentation)
Katie VishwanathMeasurement of protein aggregation levels in mutant VAPB gene in transformed yeast to determine whether ubiquitination proteasome system of the unfolded protein response can be inhibited
Primary: Greg Walsh, Secondary: John Bigbee       (Presentation)

Panel V: Friday, Dec 15, 11:00 - 12:00 PM. Harris Hall Room 3112 (see map)
Panelists: Allison Johnson, Joyce Lloyd, Rita Shiang

Ayshah AsmatAEG-1 alters methylation status of IGFBP7 promoter via activation of the Wnt/beta-catenin signaling pathway in HCC
Primary: Joyce Lloyd, Secondary: Rita Shiang       (Presentation)
Samuel YoungHormogonia mutation of touch sensitive with the removal of pili in cyanobacteria
Primary: Allison Johnson, Secondary: Joyce Lloyd       (Presentation or PDF)
Ashria AroraMeasurement of fetal gamma-globin expression due to KLF1 being a negative or positive regulator
Primary: Rita Shiang, Secondary: Allison Johnson       (Presentation)
Joshua FungDetermining if the transcription factor, Tbx5, is necessary within zebrafish myocardial regeneration (revised)
Primary: Joyce Lloyd, Secondary: Rita Shiang       (Presentation)