Introduction to Bioinformatics - Biol 591

 

SCENARIO
Identification of regulatory sites in genomic DNA
How to avoid being fooled by imposters?

The Discovery? How do you know?!?
Unfortunately, you need hard evidence that NtcA actually binds to that site before anyone will believe your theory. And hard evidence means spending the better part of a year measuring the binding of NtcA to your sequence in the test tube. If it DOESN'T bind, then you've wasted a lot of time.

Is there any way to assess the LIKELIHOOD that NtcA will bind to your sequence without actually having to do time-consuming experiments?

back to main page     back one page