MEMBRANE RECEPTORSG-PROTEIN RECEPTOR SUPERFAMILY

• MORE THAN 250 MEMBERS

• SERPENTINE GLYCOPROTEINS LOOP BACK AND FORTH THROUGH MEMBRANE

• EXTRACELLULAR DOMAIN: AMINO TERMINAL PEPTIDE AND THREE LOOPS (HYDROPHILIC REGIONS)

• IN THE MEMBRANE:SEVEN ALPHA HELICES OF ABOUT 25 HYDROPHOBIC AA

• SEE FIG 8 IN TEXT

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