CELL SIGNALLING
WHAT IS A SIGNAL?
CHEMICAL SIGNALS
ELEMENTS OF CELL SIGNALLING MECHANISMS
SIGNAL MOLECULES (FIRST MESSENGERS)
EXAMPLES OF SIGNALLING MOLECULES
RECEPTORS
LIGANDS, AGONISTS AND ANTAGONISTS
EXAMPLES OF ANTAGONISTS
REGULATION OF RECEPTOR QUANTITY AS A CONTROL MECHANISM
AN EXAMPLE OF RECEPTOR RECYCLING
MEMBRANE RECEPTORS G-PROTEIN RECEPTOR SUPERFAMILY
G-PROTEINS ARE ASSOCIATED WITH THE RECEPTORS
SOME MOLECULES THAT SIGNAL THROUGH G-PROTEIN-COUPLED RECEPTORS
SIGNAL TRANSDUCTION AT THE CELL MEMBRANE (SECOND MESSENGERS)
G PROTEINS
ADENYL CYCLASE
CYCLIC AMP ACTIVATES PROTEIN KINASES WHICH PHOSPHORYLATE PROTEINS
SOME HORMONES THAT USE C-AMP AS SECOND MESSENGER
LIGAND GATED CALCIUM CHANNELS
INOSITOL TRIPHOSPHATE AND DIACYLGLYCEROL
REMOVAL OF SECOND MESSENGERS FROM THE CYTOSOL
PROTEIN KINASES: CONFORMATIONAL CHANGES
INTRACELLULAR RECEPTORS
NEURAL NETWORKS ARE SPECIAL CASES OF SIGNALLING NETWORKS IN CELLULAR SYSTEMS
GENERALIZING NEURAL NETWORKS TO MODEL CELL SIGNALLING: D. BRAY
GENERALIZING NEURAL NETWORKS TO MODEL CELL SIGNALLING: JEFF PRIDEAUX , JOY WARE
EMERGENT PROPERTIES OF NETWORKS OF BIOLOGICAL SIGNALING PATHWAYS, BY U.S. BHALLA AND R. IYENGAR
EMERGENT PROPERTIES OBSERVED
Email: mikuleck@hsc.vcu.edu
Home Page: http://views.vcu.edu/~mikuleck/
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