REFERENCES:
Abraham, R. and J. E. Marsden (1978) Foundations of Mechanics, Benjamin/Cummings, Reading, MA.
Abraham, R. and C. D. Shaw (1982) Dynamics: The Geometry of Behavior; Part 1, Periodic Behavior, Aerial Press, Santa Cruz, CA
Abraham, R. and C. D. Shaw (1983) Dynamics: The Geometry of Behavior; Part 2, Chaotic Behavior, Aerial Press, Santa Cruz, CA
Abraham, R. and C. D. Shaw (1984) Dynamics: The Geometry of Behavior; Part 3, Global Behavior, Aerial Press, Santa Cruz, CA
Abraham, R. and C. D. Shaw (1988) Dynamics: The Geometry of Behavior; Part 4, Bifurcation Behavior, Aerial Press, Santa Cruz, CA
Abraham, R. and C. D. Shaw (1987) Dynamics: A Visual Introduction, in Yates, F. E. (ed.), Self Organizing Systems: The Emergence of Order, Plenum Press, N. Y.
Alberts, B., D. Bray, J. Lewis, M. Raff, K. Roberts, and J. D. Watson (1989) Molecular Biology of the Cell, Garland Publishing, Inc., N.Y.
Anderson, P. W. (1991) Is Complexity Physics? Is it science? What is it? Physics Today July 1991, 9-11.
Athans, M., M. L. Dertouzos, R. N. Spann, and S. J. Mason (1974) Systems, networks, and computation: Multivariable methods, McGraw-Hill, N. Y.
Auger, P. (1989) Dynamics and Thermodynamics in Hierarchically Organized Systems: Applications in Physics, Biology, and Economics, Pergamon Press, NY.
Belman, R. and K. J. Astrom (1970) On Structural Identifiability, Math. Biosci. 7: 329-339.
Biggs, N. L., E. K. Lloyd and R. J. Wilson eds. (1976) Graph Theory 1736-1936, Oxford, UK.
Blackwell, W. A. (1968) Mathematical modeling of physical networks, Macmillan, N.Y.
Blumenthal, R., S. R. Caplan and O. Kedem (1967) The Coupling of an Enzymatic Reaction to Transmembrane Flow of Electrical Current in a Synthetic "Active Transport" System, Biophys. J. 7: 735-757.
Bohm, D. (1976) Fragmentation and wholeness, Van Leer Jerusalem Fndtn.,Jerusalem.
Bohm, D. (1980) Wholeness and the Implicate Order, Routledge, Kegan and Paul, London.
Born, M. (1964) Natural Philosophy of Cause and Chance, Dover Pub., Inc., N. Y.
Branin, F. H., Jr. (1966) The Algebraic-Topological Basis for Network Analogies and the Vector Calculus, in Proceedings of the Symposium on Generalized Networks, J. Fox, ed., Wiley Interscience, N. Y.
Brayton, R. K. (1971) Nonlinear Reciprocal Networks, in Mathematical Aspects of Electrical Network Analysis, SIAM-AMS Proceedings, vol. III:1-16, Am. Math. Soc., Providence, R. I.
Breedveldt, P. C. (1984) Physical systems theory in terms of bond graphs, Ph.D. Thesis, Enschede, The Netherlands.
Bright, P. (1969) Concerning "Anisotropic" Contributions of Chemical Reactions to Flow Equations and Active Transport, J. theor. Biol. 23: 135-157.
Bunow, B. (1978) Chemical Reactions and Membranes: A macroscopic Basis for Facilitated Transport, Chemiosmosis and Active Transport. Part I: Linear Analysis, J. theor. Biol. 75: 51-78.
Callen, H. B. (1960) Thermodynamics, J. Wiley & Sons, Inc., N. Y.
Callen, H. B. (1973) Asymmetry Interpretation of Thermodynamics, in Foundations of Continuum Thermodynamics, J.J. D. Domingos, M. N. R. Nina, and J. H. Whitelaw, eds., John Wiley & Sons, N. Y., pp.61-79. (see comment by L. Tisza, p 79).
Cable, M. B., J. J. Feher and F. N. Briggs (1985) Mechanism of Allosteric Regulation of the Ca, Mg-ATPase of Sarcoplasmic Reticulum: Studies with 5'-Adenylyl Methylenediphosphate. Biochem. 24: 5612-5619.
Caplan, S. R. (1968) Autonomic Energy Conversion II. An Approach to the Energetics of Muscular Contraction, Biophys. J. 8: 1167-1193.
Caplan, S. R. (1966) The Degree of Coupling and Its Relation to Efficiency of Energy Conversion in Multiple-Flow Systems, J. theor. Biol. 10:209-235.
Caplan, S. R. and A. Essig (1983) Bioenergetics and linear nonequilibrium thermodynamics: The steady state, Harvard, Cambridge, MA.
Caplan, S. R. and D. C. Mikulecky (1966) Transport Processes in Membranes, in Ion Exchange, J. Marinsky, ed., Marcell Dekker Publ. Co. pp 1-64.
Caplan, S. R. and D. Zeilberger (1982) T. L. Hill's Graphical Method for Solving Linear Equations, Adv. Appl. Math. 3: 377-383.
Capra, F. (1982) The Turning Point: Science, Society, and the Rising Culture, Bantam, N. Y.
Carson, E. R., C. Cobelli and L. Finkelstein (1982) The Mathematical Modeling of Metabolic and Endocrine Systems: Model Formation, Identification, and Validation, J. Wiley, N. Y.
Chandrashekar, M. and F. C. Wong (1982) Thermodynamic systems analysis-I. A graph-theoretic approach, Energy 7:539-566.
Chua, L. O. (1961) Memristor- The missing circuit element, IEEE Trans. Cir. Theory CT-18: 507-519.
Chua, L. O. (1969) Introduction to Nonlinear Network Theory, McGraw-Hill, NY.
Chua, L. O. and Y. Lam (1973) A theory of algebraic n-ports, IEEE Trans. Cir. Theory CT-20: 370-381.
Chua, L. O. and P. Lin (1975) Computer - aided Analysis of Electronic Circuits: Algorithms and Computational Techniques, Prentice-Hall, Englewood Cliffs, NJ.
Chua, L. O. and R. N. Madan(1988) Sights and Sounds of Chaos, IEEE Circuits and Devices Magazine 4:3-13.
Civan, M. M. and R. J. Bookman (1982) Transepithelial Na+ Transport and the Intracellular Fluids: A Computer Study, J. Memb. Biol. 65: 63-80.
Coon, T. G. (1988) Using STELLA simulation software in life science education, in Computers in life science education 5:65-71.
Cornish-Bowden, A. (1979) Fundamentals of Enzyme Kinetics, Butterworths, London.
Cruziat, P. & Thomas, R. (1988) SPICE-a circuit simulation program for physiologists. Agronomie 8: 613-623.
deGroot, S. R. and P. Mazur (1962) Non-equilibrium Thermodynamics, North-Holland, Amsterdam.
DeRusso, P. M., R. J. Roy and C. M. Close (1965) State Variables for Engineers, Wiley, NY.
DeSimone, J. A. and S. R. Caplan (1973a) The Determination of Local Reaction and Diffusion Parameters of Enzyme Membranes from Global Measurements, Biochem. 12:3032-3039.
DeSimone, J. A. and S. R. Caplan (1973b) Symmetry and the Stationary State Behavior of Enzyme Membranes, J. theor. Biol. 39:523-544.
Desoer, C. A. and E. S. Kuh (1969) Basic Circuit Theory, McGraw-Hill, N. Y. Desoer, C. A. and G. F. Oster (1973) Globally Reciprocal Stationary Systems, Int. J. Eng. Sci. 11:141-155.
Feher, J. J. (1982) The Effect of Calcium Load on the Calcium Permeability of Sarcoplasmic Reticulum. J. Biol. Chem. 257: 10191-10199.
Feher, J. J., C. S. Fullmer and R. H. Wasserman (1992) The role of facilitated diffusion of calcium and the physiological importance of the calcium-binding affinities of calbindin in intestinal calcium absorption. Am. J. Physiol. (in press).
Fidelman, M. L. and S. Mierson (1989) Network thermodynamic model of rat lingual epithelium: effects of hyperosmotic NaCl. Am. J.Physiol. 257:G475-G487.
Fidelman, M. L. and Mikulecky (l985) The Imbalance Between Experiment and Theory in Biology: The Need for Theory Directed Modeling. Advances in Animal Welfare Science, (M.W. Fox and L.D. Mickley. eds.) pp. 202-220.
Fidelman, M. L. and D.C. Mikulecky (1986) Network Thermodynamic Modeling of Hormone Regulation of Active Na Transport in a Cultured Renal Epithelium (A6), Am. J. Physiol. 250:C978-C991.
Fidelman, M. L. & D. C. Mikulecky (1988) Network Thermodynamic Analysis and Simulation of Isotonic Solute-Coupled Flow in Leaky Epithelia: An Example of the Use of Network Theory to Provide the Qualitative Aspects of a Complex System and Its Verification by Simulation, J. theor. Biol. 130:73-93.
Fitts, D. (1962) Nonequilibrium Thermodynamics, McGraw-Hill, N.Y.
Flanders, H. (1963) Differential Forms, Academic Press, NY.
Garfinkel, D. (1984) Modeling of Inherently Complex Biological Systems: Problems, Strategies, and Methods, Math.Biosci. 72:131-140.
Gebben, V. D. (1979) Bond Graph Bibliography, J. Franklin Inst. 308:361-369.
Gibbs, J. W., (1961) The Scientific Papers of J. Willard Gibbs, Vol. I. Dover, N. Y.
Godt, R. E. and C. M. Baumgarten (1984) Potential and K+ Activity in Skinned Muscle Fibers, Biophys. J. 45:375-382.
Goldstein, L. J. and E. B. Rypins (1989) Nonlinear SPICE models for physiologic systems: Section I. Methodology. Comp. Meth. amd Prog. in Biomed. 29:161-172.
Harrary, F. (1972) Graph Theory, Addison-Wesley, Reading, MA.
Hatsapoulos, G. N. and J. H. Keenan (1965) Principles of General Thermodynamics, John Wiley & Sons, Inc., N. Y.
Heckmer, H. C. and B. Hess (1972) Analysis and Simulation of Biochemical Systems, Elsevier, Amsterdam.
Heinrich, R., M. Rapoport, and T. A. Rapoport (1977) Metabolic Regulation and Mathematical Models, Prog. Biophys.& Mol. Biol. 32:1-82.
Helferich, F. (1962) Ion Exchange, McGraw-Hill, N. Y., pp 385-389.
Hill, T. L. (1977) Free energy transduction in biology, Academic Press, N. Y. Hill, T. L. (1982) Linear Onsager coefficients for biochemical kinetic diagrams as one-way cycle fluxes, Nature 299:84-86.
Horno, J., C. F. Gonzalez-Fernandez, A. Hayas and F. Gonzalez- Caballero (1989a) Simulation of concentration polarization in electrokinetic processes by network thermodynamic methods.,Biophys. J. 55:527-535.
Horno, J., C. F. Gonzalez-Fernandez, A. Hayas and F. Gonzalez- Caballero (1989b) Application of network thermodynamics to the computer modelling of nonstationary diffusion through heterogeneous membranes, J. Memb. Sci. 42:1-12.
Huf, E. G. and J. R. Howell (1974) Computer Simulation of Sodium Fluxes in Frog Skin Epidermis, J. Memb. Biol. 15: 47-66.
Huf, E. G. & D. C. Mikulecky (1985) Compartmental Analysis of the Na+ Flux Ratio with Application to Data on Frog Skin Epidermis, J. theor. Biol 112:193-220.
Huf, E. G. & D. C. Mikulecky (1986) The role of topology in bioenergetics of sodium transport in complex epithelia, Am. J. Physiol. 250:F1107-F1118.
Imai, Y. (1989a) Membrane Transport System Modeled by Network Thermodynamics, J. Memb. Sci. 41:3-21.
Imai, Y., H. Yoshida, M. Miyamoto, T. Nakahari, and H. Fujiwara (1989b) Network Synthesis of the Epithelial transport System, J. Memb. Sci. 41:393-403.
Jacquez, J. A. (1982) The Inverse Problem in Compartmental Systems, Math. Comput. Sim. 24: 452-459. Jacquez, J. A. (1985) Compartmental analysis in biology and medicine, Univ. Mich. Press, Ann Arbor,MI.
Karnopp, D. and R. C. Rosenburg (1968) Analysis and Simulation of Multiport Systems: The Bond Graph Approach to Physical Systems, M.I.T. Press, Cambridge, MA.
Karnopp, D. and R. C. Rosenburg (1975) System Dynamics: A Unified Approach, Wiley, NY.
Katchalsky, A. and P. F. Curran (1965) Nonequilibrium thermodynamics in biophysics, Harvard Univ. Press, Cambridge, MA.
Kay, J. J. (1984) The thermodynamics of self organizing systems, Ph.D. thesis, Univ. Waterloo, Canada.
Kay, J. J. and E. D. Schneider (1992) Life as a Phenomenological Manifestation of the Second Law of Thermodynamics, in Advances in Mathematics and Computers in Medicine vol. 6: (D. C. Mikulecky and M. Witten, eds.), Pergamon Press, (in press).
Kedem, O. and S. R. Caplan (1965) Degree of coupling and its relation to efficiency of energy conversion. Trans. Faraday Soc. 61:1897-1911.
Kedem, O. and A. Katchalsky (1958) Thermodynamic Analysis of the Permeability of Biological Membranes to Non-electrolytes, Bioch. Biophys. Acta 27: 229-246.
Kedem, O. and A. Katchalsky (1961) A Physical Interpretation of the Phenomenological Coefficients of Membrane Permeability, J. Gen. Physiol. 45: 143-179.
Kedem, O. and A. Katchalsky (1963a) Permeability of composite membranes: Part l.-Electric current flow and flow of solute through membranes. Trans. Faraday Soc. 59:1918-1930.
Kedem, O. and A. Katchalsky (1963b) Permeability of composite membranes: Part 2.-Parallel elements, Trans. Faraday Soc. 59:1931-1940.
Kedem, O. and A. Katchalsky (1963c) Permeability of composite membranes: Part 3.-Series array of elements, Trans. Faraday Soc. 59:1941-1953.
King, E. L. and Altman, C. (1956) A schematic method of deriving the rate laws for enzyme catalized reactions, J. Phys. Chem. 60:1375-1378.
Kirchhoff, G. R. (1847) On the solution of the equations obtained from the investigation of the linear distribution of galvanic currents, English translation in Graph Theory 1736-1936, N.L. Biggs, E.K. Lloyd and R.J. Wilson eds. Oxford, 1976.
Koenig, H. E., Tokad, Y., Kesevan, H. K. (1967) Analysis of Discrete Physical Systems, McGraw-Hill, N. Y.
Lang, S. (1968) Analysis I, Addison-Wesley, Reading, MA.
Lang, S. (1973) Calculus of Several Variables, Addison-Wesley, Reading, MA.
Lew, V. L., H. G. Ferreira and T Moura (1979) The Behavior of Transporting Epithelial Cells: 1. Computer Analysis of a Basic Model, Proc. Roy. Soc. London B 206: 53-83.
MacDonald, N. (1983) Trees and Networks in Biological Models, Wiley, N. Y.
MacFarlane, A. G. J. (1970) Dynamic System Models, Harrap, London.
MacInnes, D. A. (1939) The Principles of Electrochemistry, Reprinted by Dover, NY, 1961.
Maddox, J. (1991) Is Darwinism a Thermodynamic Necessity? Nature 350:653.
Mandel, J. E. (1989) A comparison of three graphically oriented simulation environments for the Macintosh, in Computers in life science education 6:57-63.
Margenau, H. and G. M. Murphy (1957) The Mathematics of Physics and Chemistry, Van Nostrand, Princeton, N. J.
Marti, J. (1991) Chaos May Be the New World Order, Utne Reader 48:30-32.
Mason, S. J. and H. J. Zimmermann (1960) Electronic circuits, signals, and systems, Wiley, N.Y.
May, J. M. and D. C. Mikulecky (1982) The Simple Model of Adipocyte Hexose Transport: Kinetic Features, Effect of Insulin, and Network Thermodynamic Computer Simulations, J. Biol. Chem. 257:11601-11608.
May, J. M. and D. C. Mikulecky (1983) Glucose Utilization in Rat Adipocytes: The Interaction of Transport and Metabolism as Affected by Insulin, J. Biol. Chem. 258:4771-4777.
Meixner, J. (1963) Thermodynamics of Electrical Networks and the Onsager-Casimir Reciprocal Relations, J. Math. Physics 4:154-159.
Meixner, J. (1966) Network Theory in its Relation to Thermodynamics, in Proceedings of the Symposium on Generalized Networks, J. Fox, ed., Wiley Interscience, NY, pp 13-25.
Mierson, S. and M. L. Fidelman (1992) The Role of Epithelial Ion Transport in Taste Transduction: A Network Thermodynamic Model, in Advances in Mathematics and Computers in Medicine vol. 6: (D. C. Mikulecky and M. Witten, eds.), Pergamon Press, (in press).
Mikulecky, D. C. (1969) Biological Aspects of Transport, in Transport Phenomena in Fluids (H. J. M. Hanley, ed.), Dekker, NY, pp 433-494.
Mikulecky, D. C. (1977) A Simple Network Thermodynamic Method for Modeling Series-Parallel Coupled Flows: II. The Nonlinear Theory with applications to Coupled Solute and Volume Flow in a Series Membrane., J. theor. Biol. 69, 511-542.
Mikulecky, D. C. (1979) A network thermodynamic 2-port for coupled salt and current flow. An improvement over equivalent circuit models, Biophys. J. 25:323-339.
Mikulecky, D. C.(1980) The use of a circuit simulation program (SPICE2) to model the microcirculation in Biofluid Mechanics Vol. 2 (Daniel J. Schneck, ed.) pp. 327-345.
Mikulecky, D. C.(1983a) Network Thermodynamics: A Candidate for a Common Language for Theoretical and Experimental Biology, Am. J. Physiol. 245:Rl-R9.
Mikulecky, D. C.(1983b) A Network Thermodynamic Approach to the Hill-King & Altman Approach to Kinetics: Computer Simulation. In: Membrane Biophysics II: Physical Methods in the Study of Epithelia (M. Dinno A.B. Calahan and T.C. Rozzell eds.) A.R. Liss, NY, pp 257-282.
Mikulecky, D. C.(1984) Network Thermodynamics: A Simulation and Modeling Method Based on the Extension of Thermodynamic Thinking into the Realm of Highly Organized Systems, Math. Biosci. 72:157-179.
Mikulecky, D. C. (1985) Network Thermodynamics in Biology and Ecology: An Introduction, in Ecosystem Theory for Biological Oceanography (R. E. Ulanowicz and T. Platt, eds.) Canadian Bull. Fisheries and Aq. Sci. 231:163-175.
Mikulecky, D. C. (1987a) Simulation of the Mitochondrial Energy Transduction Mechanism: Is Chemiosmosis Local or Global? in Simulators IV, Soc. Comp. Sim. Int'l., Piscataway, N. J., pp 94-96.
Mikulecky, D. C. (1987b) Topological Contributions to the Chemistry of Living Systems. in Graph Theory and Topology in Chemistry, (R. B. King and D. H. Rouvray, eds.) Elsevier, N. Y. pp. 115-123.
Mikulecky, D. C. (1987c) Network thermodynamics and complex systems theory: An approach to understanding the relationship between structure and function in biological systems, in Network Thermodynamics, Heat and Mass Transfer in Biotechnology, Proc. ASME 1987 Winter Annual Meeting, pp 1-8.
Mikulecky, D. C. (1988a) When Is a Mechanism Not a Mechanism? The Network Thermodynamic Approach to Complex Systems. Mathl. & Comput. Modeling 11:464-468.
Mikulecky, D. C. (1988b) Some Applications of the Current Divider Principle to Physical Networks: A Network Thermodynmic Approach to a "Biological" Circuit Theory. Proc. IEEE Southeastcon. '88, pp 424-429.
Mikulecky, D. C. (1988c) Simulation of Nonlinear Kinetic and Compartmental Systems Using the Reference State: An Application of Peusner's Network Thermodynamics, Simulators V,Soc. Comp. Sim. Int'l., Piscataway, N. J., pp 391-394.
Mikulecky, D. C. (1991) Network Thermodynamics: A Unifying Approach to Dynamic Nonlinear Living Systems, in Theoretical Ecosystems Ecology: The Network Perspective, T. P. Burns and M. Higashi,(eds.),Cambridge Univ. Press, pp 71-100.
Mikulecky, D. C., W.A. Wiegand and J.S. Shiner (1977) A Simple Network Thermodynamic Method for Modelling Series- Parallel Coupled Flows: I. The Linear Case. J. Theoret. Biol. 69: 47l-5l0.
Mikulecky, D. C. and S. R. Thomas (1979) Some network thermodynamic models of coupled, physiological systems, J. Franklin Inst. 308: 309-325.
Mikulecky, D. C., E. G.Huf and S. R. Thomas (1979) A network thermodynamic approach to compartmental analysis: Na+ transients in frog skin, Biophys. J. 25:87-105.
Mikulecky, D. C. and F. A. Sauer (1988) The role of the reference state in nonlinear kinetic models: Network thermodynamics leads to a linear and reciprocal coordinate system far from equilibrium. J. Math. Chem. 2:171-196.
Mikulecky, D. C., W. A. Thedford and J. A. DeSimone (1977) Local vs. Global Reciprocity and an analysis of the Teorell Membrane Oscillator Using Catastrophe Theory: Part I, Reciprocity and Bifurcation, Biophys. Memb. Transp. 3: 75-118.
Miller, D. G. (1960) Thermodynamics of Irreversible Processes. The Experimental Verification of the Onsager Reciprocal Relations, Chem. Revs. 60:15.
Miller, D. G. (1969) The Experimental Verification of the Onsager Reciprocal Relations, in Transport Phenomena in Fluids (H. J. M. Hanley, ed.), Dekker, NY, pp 377-432.
Mintz, E., S. R. Thomas and D. C. Mikulecky (1986a) Expoloration of Apical Sodium Transport Mechanisms in an Epithelial Model by Network Thermodynamic Simulation of the Effect of Mucosal Sodium Depletion: I. Comparison of Three Different Apical Sodium Permeability Mechanisms, J. Theor. Biol. 123:1-19.
Mintz, E., S. R. Thomas and D. C. Mikulecky (1986b) Expoloration of Apical Sodium Transport Mechanisms in an Epithelial Model by Network Thermodynamic Simulation of the Effect of Mucosal Sodium Depletion: II. An Apical Sodium Channel and Amiloride Blocking, J. Theor. Biol. 123:21-34.
Misner, C. W., K. S. Thorne and J. A. Wheeler (1973) Gravitation, Freemen, San Francisco, CA. Nicholas, G. and I. Prigogine (1977) Self Organization in Nonequilibrium Systems: From Dissipative Structures to Order Through Fluctuations, John Wiley & Sons, NY.
Oken, D. E., S. R. Thomas and D. C. Mikulecky (1981) A Network Thermodynamic Model of Glomerular Dynamics: Application in the Rat, Kidney Int. 19: 359-373.
Onsager, L. (1931a) Reciprocal Relations in Irreversible Processes I, Phys. Rev. 37: 405-426.
Onsager, L. (1931b) Reciprocal Relations in Irreversible Processes II, Phys. Rev. 38: 2265-2279.
Oster, G. F., A. Perelson and A. Katchalsky (1971) Network Thermodynamics, Nature 234:393-399 (See editorial:"Networks in Nature, pp 380-381, same issue).
Oster, G. F., A. Perelson and A. Katchalsky (1973) Network thermodynamics:dynamic modelling of biophysical systems, Quart. Rev. Biophys. 6:1-134.
Oster, G. F. and C. A. Desoer (1971) Tellegen's Theorem and Thermodynamic Inequalities, J. theor. Biol. 32: 219-241.
Oster, G. F. and A. S. Perelson (1973) Systems, Circuits, and Thermodynamics, Israel J. Chem. 11: 445-478.
Oster, G. F. and D. M. Auslander (1971a) Topological Representations of Thermodynamic Systems-I. Basic concepts, J. Franklin Inst. 292: 1-13.
Oster, G. F. and D. M. Auslander (1971b) Topological Representations of Thermodynamic Systems-II. Some Elemental Subunits for Irreversible Thermodynamics, J. Franklin Inst. 293: 77-90.
Oster, G. F. and A. S. Perelson (1974) Chemical Reaction Dynamics. Part I: Geometrical Structure, Arch. Rational Mech. Anal. 55: 230-274.
Patlak, C. S., D. A. Goldstein, and J. F. Hoffman (1963) The Flow of Solute and Solvent Across a Two Membrane System, J. theor. Biol. 5:426-442.
Peacocke, A. R. (1983) An introduction to the physical chemistry of biological organization, Clarendon Press, Oxford.
Peacocke, A. R. (1985) Reductionism in academic disciplines, SRHE & NFER-Nelson, Surrey.
Penfield, P., Jr., R. Spence, & S. Duinker (1970) Tellegen's Theorem and Electrical Networks; Research Mon.# 58, M.I.T. Press, Cambridge, MA.
Perelson, A. S. (1975) Network Thermodynamics: An Overview, Biophys. J. 15: 667-685.
Perelson, A. S. and G. F. Oster (1974) Chemical Reaction Dynamics. Part II: Reaction Networks, Arch. Rational Mech. Anal. 57: 31-98.
Perelson, A. S. (1988) Toward a Realistic Model of the Immune System, in Theoretical Immunology (A. S. Perelson, ed.), Addison-Wesley, Redwood City, CA, pp 377-401.
Peusner, L. (1970) The principles of network thermodynamics and biophysical applications, Ph. D. thesis, Harvard. Univ., Cambridge, MA. [Reprinted by Entropy Limited, South Great Road, Lincoln, MA 01773,1987]
Peusner, L. (1982) Global Reaction-diffusion Coupling and Reciprocity in Linear Asymmetric Networks, J. Chem. Phys. 77:5500-5507.
Peusner, L. (1983a) Electrical network representation of n-dimensional chemical manifolds, in Chemical applications of topology and graph theory (R.B. King,ed), Elsevier, Amsterdam.
Peusner, L. (1983b) Hierarchies of irreversible energy conversion systems I. Linear steady state without storage J. Theor. Biol. 102:7-39.
Peusner, L. (1985a) Hierarchies of irreversible energy conversion systems II. Network derivation of linear transport equations, J. Theor. Biol. 115:319-335.
Peusner, L. (1985b) Network thermostatics, J. Chem. Phys. 83:1276-1291.
Peusner, L. (1985c) Premetric thermodynamics: A topological graphical model, J. Chem. Soc., Faraday Trans. 2;81:1151-1161.
Peusner, L. (1986a) Hierarchies of irreversible energy conversion systems III. Why are Onsager's equations reciprocal? The Euclidean geometry of fluctuation-dissipation space, J. Theor. Biol. 122:125-155.
Peusner, L. (1986b) Studies in network thermodynamics, Elsevier, Amsterdam.
Peusner. L., D. C. Mikulecky, S. R. Caplan, and B. Bunow (1985) Unifying Graphical Approaches to Dynamic Systems: Network Thermodynamics, Hill and King Altman Diagrams in Reaction- Diffusion Kinetics, J. Chem. Phys. 83:5559-5566.
Pohunjapalo, H. and B. Wahlstrom (1982) Software for Solving Identification and Identifiability Problems, Math. Comput. Sim. 24: 490-493.
Prideaux, J. A. (1992) A Systems Approach to Modelling and Simulating the Interactions between Cells in a Solid Tumor, Master's Thesis, Virginia Commonwealth University, Richmond, VA.
Prideaux, J. A., J. L. Ware, A. M. Clarke, and D. C. Mikulecky (1992) From Neural Networks to Cell Signalling: Chemical Communications among Cell Populations, Proc. 14th Ann. Conf. IEEE Eng. Med. Biol. Soc. (in press).
Prigogine, I. (1961) Thermodynamics of Irreversible Processes, John Wiley & Sons, N. Y. Prigogine, I. and R. Defay (1965) Chemical Thermodynamics, Longmans, Green, and Company, London.
Rashevsky, N. (1954) Topology and life:In search of general mathematical principles in biology and sociology, Bull. Math. Biophys. 16:317- 349.
Richardson, I. W., A. H. Louie, & S. Swaminathan (1982) A phenomenological calculus for complex systems. J. theor. Biol. 94:61-76.
Richmond, B., S. Peterson and P. Vescuso (1987) An academic users guide to STELLA, High Performance Systems, Inc., Lyme, N. H. 03768.
Rideout, V. C. (1991) Mathematical and Computer Modeling of Physiological Systems, Prentice Hall, Englewood Cliffs, NJ.
Roe, P. H. (1966) Networks and Systems, Addison-Wesley, Reading, MA.
Rose, S., L. J. Kamin & R. C. Lewontin (1984) Not in Our Genes: Biology, Ideology, and Human Nature, Penguin, N. Y.
Rose, H. and S. Rose, eds.(1976) Ideology of/in the Natural Sciences, Shenkman, Cambridge, MA.
Rosen, R. (1978) Fundamentals of Measurement and Representation of Natural Systems, North-Holland, Amsterdam.
Rosen, R. (1985a) Information and complexity, in Ecosystem theory for biological oceonography, Canadian Bull. Fish. and Aquat. Sci. 213:221-233.
Rosen, R. (1985b) Organisms as casual systems which are not mechanisms: An essay into the nature of complexity, in Theoretical Biology and Complexity, R. Rosen, ed. Academic Press, N.Y.
Rosen, R. (1985c) Anticipatory Systems, Pergamon, London.
Rosen, R. (1972) Some systems theoretical problems in biology, in The Relevance of General Systems Theory (E. Laszlo, ed.), George Braziller, N. Y.
Rosen, R. (1991) Life Itself, Columbia Univ. Press, NY. Roszak, T. (1974) The monster and the titan: Science, Knowledge, and Gnosis, in Science and its Public: The Changing Relationship, Proc. Am. Acad. Arts and Sci. 103:17-32.
Rothschild, K. J., S. A. Ellias, A. Essig and H. E. Stanley (1980) Nonequilibrium Linear Behavior of Biological Systems: Existence of Enzyme-Mediated Multidimensional Inflection Points, Biophys. J. 30: 209-230.
Sauer, F. A. (1973) Nonequilibrium thermodynamics of kidney tubule transport, in Appendix to Chapter 12, Handbook of Physiology, Section 8, (J. Orloff & r. w. Berliner, eds) Williams and Wilkins, Baltimore, MD, pp. 399-414.
Sauer, F. A. (1975) Thermodynamics of membrane transport, in Intestinal Permeation (M.Kramer and F.Lauterbach, eds.) Exerpta Medica,Amsterdam. Schneck, D. J. (1990) Engineering Principles of Physiologic Function, N.Y.U. Press, N. Y.
Seshu, S. and M.B. Reed (1961) Linear graphs and electrical networks, Addison-Wesley, Reading, MA. Schnakenburg, J. (1977) Thermodynamic network analysis of biological systems, Springer-Verlag, N.Y.
Seither, R. L., D. F. Trent, D. C. Mikulecky, T. J. Rape and I. D. Goldman (1989) Folate-Pool Interconversions and Inhibition of Biosynthetic Processes after Exposure of L1210 Leukemia Cells to Antifolates, J. Biol. Chem. 264: 17016-17023.
Seither, R. L., D. Hearne, D. Trent, D. C. Mikulecky and I. D. Goldman (1990) SPICE2 network thermodynamic simulation of antifolate effects on purine and pyrimadine biosynthesis: exploring the role of tetrahydrofolate cofactor depletion versus dihydrofolate feedback inhibition, Computers Math. Applic. 20:87-101.
Seither, R. L., D. F. Trent, D. C. Mikulecky, T. J. Rape and I. D. Goldman (1991) Effect of Direct Suppression of Thymidylate Synthetase at the 5,10-Methylenetetrahydrofolate Binding Site on the Interconversion of Tetrahydrofolate Cofactors to Dihydrofolate by Antifolates, J. Biol. Chem. 266:4112-4118.
Sneddon, I. N. (1957) Elements of Partial Differential Equations, McGraw- Hill, N. Y.
Strange, K. and K. R. Spring (1986) Methods for Imaging Renal Tubule Cells, Kidney Int. 30: 192-200.
Stucki, J. W. (1980) The Thermodynamic Buffer Enzymes, Eur. J. Biochem. 109: 257.
Talley, D. B., J. P. Ornato and A. M. Clarke (1990) Computer-aided Characterization of the Thumper Compression Waveform in Closed-chest CPR, Biomed. Inst. Tech. July/August, 283-288.
Tellegen, B. D. H. (1952) A general network theorem with applications, Phillips Res. Rep. 7:259-269.
Teorell, T. (1959) Electrokinetic Membrane Processes in Relation to Properties of Exciteable Tissues: I. Experiments on Oscillating Transport Phenomena in Artificial Membranes, J. Gen Physiol. 42: 831-845.
Teorell, T. (1959) Electrokinetic Membrane Processes in Relation to Properties of Exciteable Tissues: II. Some Theoretical Cosiderations, J. Gen Physiol. 42: 847-863.
Teorell, T. (1953) Transport Processes and Electrical Phenomena in Ionic Membranes, Prog. Biophys. 3: 305-369.
Thakker, K. M., J. H. Wood and D. C. Mikulecky (1982) Dynamic Simulation of Pharmacokinetic Systems Using the Electrical Circuit Analysis Program SPICE2. Comp. Prog. Biomed. 15:61- 72.
Thakker, K. M. and D. C. Mikulecky (1985) Modelling and Simulation of the Nonlinear Dose-Plasma Concentration Response of Phenylbutazone on Periodic Multiple Oral Dosing: A Mechanistic Approach. Mathematical Modelling, 7:1181-1186(1986).
Thoma, J. U. (1975) Introduction to bond graphs and their applications, Pergamon, N. Y.
Thomas S. R. and Mikulecky D. C. (1978) A network theromodynamic model of salt and water flow across the kidney proximal tubule, Am. J. Physiol. 235: F638-F648.
Tisza, L. (1977) Generalized Thermodynamics, MIT Press, Cambridge, MA.
Truesdell, C. (1969) Rational Thermodynamics, McGraw-Hill, NY.
Tuinenga, P. W. (1988) SPICE: A guide to circuit simulation and analysis using PSpice. Prentice Hall, N. J.
Ulanowicz, R. E. (1986) Growth and Development: Ecosystem Phenomenology, Springer-Verlag, N. Y.
Walter, E. (1982) Identifiability of State Space Models, Springer-Verlag, N. Y.
Weinhold, F. (1975) Metric geometry of equilibrium thermodynamics. J. Chem. Phys. 63:2479-2483.
Walz, D. (1990) Biothermokinetics of Processes and Energy Conversion, Biochim. Biophys. Acta 1019: 171-224.
Walz, D., S. R. Caplan, D. R. L. Scriven and D. C. Mikulecky (1992) Methods of Bioelectrochemical Modelling, in Treatise on Bioelectrochemistry, (G. Millazzo, ed.) Birkhauser, (in press).
Weiss, P. A. (1969) The Living System: Detyerminism Stratified, in Beyond Reductionism: New Perspectives in the Life Sciences, (A. Koestler and J. R. Smythies, eds), Beacon Press, boston, MA, pp 3-55.
Westerhoff, H. V. and K. van Dam (1987) Thermodynamics and Control of Biological Free-energy Transduction, Elsevier, Amsterdam.
White J. C. (1979) Reversal of methotrexate binding to dihydrofolate reductase by dihydrofolate : Studies with pure enzyme and computer modeling using network thermodynamics, J. Biol. Chem. 254:10889-10895.
White J. C. and Mikulecky D. C. (1981) Application of network thermodynamics to the computer modeling of the pharmacology of anticancer agents: A network model for methotrexate action as a comprehensive example, Pharmacol. Ther. 15: 251-291.
White, J. C. (1986) Use of the Circuit Simulation Program SPICE2 for Analysis of the Metabolism of Anticancer Drugs, Bull Math. Biol. 48: 353-380.
Wyatt, J. L. (1978) Network Representation of Reaction-diffusion Systems Far From Equilibrium, Comp. Prog. Biomed. 8: 180-195.
Wyatt J.L., Mikulecky D. C. and De Simone J. A. (1980) Network modeling of reaction-diffusion systems and their numerical solutions using SPICE, Chem. Eng. Sci. 35: 2115-2128.
Yates, F. E. (1987) Self Organizing Systems: The Emergence of Order, Plenum Press, N. Y.
Yates, F. E. (1992) Order, Complexity, and Self-Organization in Dynamic Systems: Outline of a Generalized Mechanics for Biology, in Advances in Mathematics and Computers in Medicine vol. 6: (D. C. Mikulecky and M. Witten, eds.), Pergamon Press, (in press).