Study Guide II - Labeling and TLC
What about
99m
Tc?
What are the different states?
Why and how is it reduced?
Name several reducing agents and which one is the most popular?
How is bound technetium compound re-oxidize?
What are the different impurities found in solution of bound technetium?
What is a a ligand exchange (or transchelation / give an example.
What by-product occurs with stannous ion when there is too much tin in solution?
What happens to the compounding process if there is too little stannous ion?
What is the ratio of the reducing agent to the pertechnetate?
Define bifunctional
Cheaters
. Give an example.
Consider the role of
99
Tc and
99m
Tc ratios and the application when you apply the T
1/2
.
Identify the three method and the protocols to labeling RBCs.
Related to Hot Lab QC be able to complete the following calculations
Constancy
Accuracy
Geometric Variation
Linearity
CPM to DPM on a well counter
Other parts of the up and coming exam will include:
Identify the different forms of radiopharmaceutical biodistribution.
Identify the properties of pertechnetate and determine why it is an "ideal" radioisotope.
Calculate the amount of pertechnetate available several hours after the initial morning elution.
Know your half-lives, which include but not limited to:
123
I,
201
Tl,
99
Mo,
137
Cs,
99m
Tc,
18
F,
68
Ge, and
57
Co
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11/23