Drugs That May Affect or Alter Radiopharmaceutical Distribution of Gallium-67
|
Causative Drug | Appearance on Scintiphotos |
Adrenocorticosteroids | Decreased brain uptake |
Aminoglycosides |
Diffuse kidney, colon, breast and/or bone uptake |
Amiodarone | Lung uptake |
Arnpicillin |
Diffuse kidney, colon and; or breast uptake |
BCG | Liver and/or lung uptake |
Bleomycin |
Diffuse kidney and/or lung uptake; gastric uptake |
Busulfan | Lung uptake |
Calcium gluconate |
Muscle, skin, connective tissue and soft tissue uptake |
Cephalexin | Diffuse kidney uptake |
Cephalosporins |
Diffuse kidney, colon and/or breast uptake |
Chlorpromazine | Symmetrical breast uptake |
Cisplatin |
Kidney and gastric uptake; decreased tumor/abscess uptake |
Clindarnycin | Diffuse kidney and/or colon uptake |
Cyclophosphamide | Thymic, lung and/or renal uptake |
Dialysate | Intense skeletal uptake |
Diethylstilbesterol | Symmetrical breast uptake |
Digitalis | Symmetrical breast uptake |
Doxorubicin |
Diffuse kidney and/or colon uptake; gastric uptake |
Estrogen therapy |
Symmetrical breast uptake (nonneoplastic) |
Furosemide | Diffuse kidney and/or colon uptake |
Gentamicin | Thymic uptake |
Imipramine | Symmetrical breast uptake |
Iron dextran |
Liver uptake and decreased abscess uptake |
Methotrexate |
Increase kidney, lung and/or bone uptake; decreased tumor/abscess uptake |
Nitrofurantoin | Lung uptake |
Penicillin | Thymic uptake |
Phenobarbital | Diffuse kidney uptake and liver uptake |
Phanylbutazone | Diffuse kidney uptake |
Phenytoin |
Diffuse kidney uptake; mimics lymphoma-like pattern |
Prednisone |
Thymic and soft tissue uptake (whole body retention) |
Reserpine | Symmetrical breast uptake |
Sulfonamides | Diffuse kidney uptake |
Thiazides | Diffuse kidney uptake |
Vincristine |
Increased bone, lung, and thymic uptake; increased renal elimination; decreased tumor/abscess uptake |
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