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Drugs That May Affect or Alter Radiopharmaceutical
Distribution in Lung Perfusion (99mTcMAA) and
Lung Ventilation (133Xe gas) Imaging Studies
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| Causative Drug | Appearance on Scintiphotos |
| Alcohol | Retention of 133Xe in liver |
Bleomycin |
Focal areas of decreased lung uptake of 99mTcMAA |
| Bronchoconstricting agents | Focal areas of decreased lung uptake of 133Xe |
| Bronchodilating agents |
Improved 133Xe uptake and clearance; mimics pulmonary emboli |
| Busulfan | Focal areas of decreased lung uptake of 133Xe |
| Clofibrate | Retention of 133Xe in liver and focal areas in lungs |
| Diazepam | Improved uptake/clearance of 133Xe |
| Heparin | Mimics pulmonary emboli |
| Intravenous Hyperalimentation | Liver uptake of 133Xe |
| Methotrexate | Focal areas of decreased lung uptake |
| Methyfsergide | Focal areas of decreased lung uptake |
| Narcotic addiction | Diffuse, non segmental defects with 99mTcMAA and delayed clearance with 133Xe |
| Nitrofurantoin | Focal areas of decreased lung uptake |
| Terbutaline | Improved 133Xe uptake and clearance |
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