Cardiovascular and sympathomimetic drugs

Antiarrhythmics for ventricular arrhythmias

Amiodarone

Not practical to withdraw

1,3

Combined α/β-blocker

Labetalol

72 hours

1,3

Adrenergic neurone blockers

Bretylium

48 hours

2,3

Guanethidine

48 hours

2,3

Reserpine

48 hours

2,3

α-Blocker

Phenoxybenzamine (intravenous doses only)

15 days

5

Calcium channel blockers

Amlodipine

48 hours

4,5

Diltiazem

24 hours

4,5

Felodipine

48 hours

4,5

Isradipine

48 hours

4,5

Lacidipine

48 hours

4,5

Lercanidipine

48 hours

4,5

Nicardipine

48 hours

4,5

Nifedipine

24 hours

4,5

Nimodipine

24 hours

4,5

Nisoldipine

48 hours

4,5

Verapamil

48 hours

4,5

Inotropic sympathomimetics

Dobutamine

24 hours

3

Dopamine

24 hours

3

Dopexamine

24 hours

3

Vasoconstrictor sympathomimetics

Ephedrine

24 hours

1

Metaraminol

24 hours

3

Norepinephrine

24 hours

3

Phenylephrine

24 hours

3

β2 stimulants (sympathomimetics)

Salbutamol

24 hours

3

Terbutaline

24 hours

3

Eformoterol

24 hours

3

Bambuterol

24 hours

3

Fenoterol

24 hours

3

Salmeterol

24 hours

3

Other adrenoreceptor stimulants

Orciprenaline

24 hours

3

Systemic and local nasal decongestants, compound cough and cold preparations

Pseudoephedrine

48 hours

3

Phenylephrine

48 hours

3

Ephedrine

24 hours

1

Xylometazoline

24 hours

3

Oxymetazoline

24 hours

3

Sympathomimetics for glaucoma

Brimonidine

48 hours

3

Dipivefrine

48 hours

3

Neurological drugs

Antipsychotics (neuroleptics)

Chlorpromazine

24 hours

1

Benperidol

48 hours

1

Flupentixol

48 hours, or 1 month for depot

1

Fluphenazine

24 hours, or 1 month for depot

1

Haloperidol

48 or 1 month for depot

1

Levomepromazine

72 hours

1

Pericyazine

48 hours

1

Perphenazine

24 hours

1

Pimozide

72 hours

1

Pipotiazine

1 month for depot

1

Prochlorperazine

24 hours

1

Promazine

24 hours

1

Sulpiride

48 hours

1

Thioridazine

24 hours

1

Trifluoperazine

48 hours

1

Zuclopenthixol

48 hours, or 1 month for depot

1

Amisulpride

72 hours

1

Clozapine

7 days

1

Olanzapine

7–10 days

1

Quetiapine

48 hours

1

Risperidone

5 days or 1 month for depot

1

Sertindole

15 days

1

Zotepine

5 days

1

Sedating antihistamines

Promethazine

24 hours

1

Opioid analgesics

Tramadol

24 hours

1

Tricyclic antidepressants

Amitriptyline

48 hours

1

Amoxapine

48 hours

1

Clomipramine

24 hours

1

Dosulepin (dothiepin)

24 hours

1

Doxepin

24 hours

1

Imipramine

24 hours

1

Lofepramine

48 hours

1

Nortriptyline

24 hours

1

Trimipramine

48 hours

1

Tricyclic-related antidepressants

Maprotiline

48 hours

1

Mianserin

48 hours

1

Trazolone

48 hours

1

Venlaflaxine

48 hours

1

Mirtazepine

8 days

1

Reboxetine

3 days

1

CNS stimulants

Amphetamines, e.g. dexamfetamine

48 hours

3

Atomoxetine

5 days

1

Methylphenidate

48 hours

5

Modafinil

72 hours

5

Cocaine

24 hours

1

Caffeine

24 hours

5