Gastric Emptying Calculations

  1. There is a lot more to discuss than what is printed here, when it comes to GES procedures. We will cover the details in the Fall. For now let us understand the math behind the procedure noting the the patient has consumed a radioactive meal
  2. Technical Factors to consider when performing a gastric emptying study
    1. Positioning
      1. Personnel preference based on equipment available
      2. My suggestion, based on a two-headed camera system, if the patient can be imaged upright, then this would be the method of choice, taking both anterior and posterior images at the same time
    2. Image acquisition and correction for decay
      1. Following the administration of a radioactive meal, preferably solid, ANT and POST images are taken immediately after the patient has eaten
      2. Initial images are labeled as zero time
        1. Regions of interest are drawn over the stomach in both images and the counts are recorded
        2. gesgeomean.jpg - 4914 Bytes

        3. ANT counts and POST counts are used to determine the geometric mean using the above diagram
        4. As an example, let’s say that ANT counts = 20,500 and POST counts = 21,500.
        5. Applying the geometric mean formula would give you a value at time zero of 21,994 counts
      3. Images are then taken every 30 minutes for up to 2.5 hours
        1. ROIs are then drawn over the ANT and POST stomach and counts are recorded
        2. gesgeomean.jpg - 4914 Bytes

        3. Using the above diagram, again determine the geometric mean for each set of images taken
        4. These counts must then be relate (decayed) back to time zero
        5. How is this done?
          1. It is important to realize that you must decay back to the past, to time zero, which means you have to divide geometric mean by the appropriate decay factor
          2. Several clinics have known to multiple the geometric mean by the decay factor – Don’t Do This!
          3. Applying the correct approach the geometric mean is calculated and then the decay factor is applied
          4. gesformula.jpg - 6515 Bytes

          5. Notice from the formula that the technetium decay factor is divided into the geometric mean, which allows you to relate the time in which the images where taken back to zero time
          6. As an example, if you have a geometric mean of 10,000 counts and an hour has passed from time zero, then the decay factor is 0.891
          7. The one hour decay factor is then divided into 10,000 counts giving you a value of 11,223 counts
      4. Now you need to determine the gastric emptying time at 1 hour
        1. percentremaining.jpg - 9289 Bytes

        2. Using the examples given above and noting the diagram, you must divide 11,223 counts into 21,994 counts and then multiple by 100
        3. This value is 51%, which means that this is the amount of the radio-meal that remains in the stomach
        4. percentemptied.jpg - 4168 Bytes

        5. To determine the amount emptied apply the above example
        6. Hence, 100% - 51% = 49% emptied
      5. For each ANT/POST counts collected you must determine what the % emptying is by applying the above examples for each time collected
  3. Review of an example gastric emptying exam
    1. gastricemtabn.jpg - 59479 Bytes

    2. The above images show images and ROIs from a procedure in which a patient consumed 855 μCi of Radio Colloid eggs. Images were taken immediately after the meal was eaten and then every ½ hour for 2.5 hours
    3. Not all images are displayed, however, appropriate data is displayed as a sample study

    4. Example of Gastric Emptying Calculations
      Review the calculations below – you will see them again

      Times and decay factors

      Anterior cts

      Ant x Post
      Decay Factor

      Current Time x100
      Zero Time

      % Remaining

      % Emptied
      (100 - %E)

      Posterior cts

      0 Minutes (df – 1.000)

      A = 31.0 k

      1553 k/1.0

      39.4/39.4 x 100

      100

      0

      P = 50.1 k

      30 Minutes (df – 0.944)

      A =31.5 k

      1499 k/0.944

      41/39.4 x 100

      104

      0

      P =47.6 k

      60 Minutes (df – 0.891)

      A = 44.7 k

      1153 k/0.891

      38.1/39.4 x 100

      96

      4

      P = 25.8 k

      120 Minutes (df – 0.794)

      P =10.7 k

      266 k/0.794

      20.5 k/39.4k x100

      52

      48

      A = 24.9 k

      150 Minutes (df – 0.750)

      P =1.8 k

      10.8 k/ 0.750

      4.3 k/0.75 x 100

      11

      89

      A = 5.7 k



     

     

     

     

     

     

     

     

     

     

    gescurves.jpg - 45951 Bytes

  4. Time activity curves can be drawn, which are seen above
  5. Gastric Emptying Work Sheet
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