Biol 591 
Introduction to Bioinformatics
Problem Sets
Fall 2002 

Introduction

Problem Set IntroM: Molecular Biology
Problem Set IntroP: Computer/Programming
Scenario 1: Identification of a possible regulatory site in genomic DNA
Problem Set 1M: Molecular Biology
Problem Set 1P: Programming/Bioinformatic tools
Scenario 2: Comparison of genomes to look for genes responsible for pathogenesis
Problem Set 2M: Molecular Biology
Problem Set 2P: Programming/Bioinformatic tools
Scenario 3: Mystery of the missing match: Sequence alignment
Problem Set 3: Bioinformatics/programming
Scenario 4: Metabolic modeling
Problem Set 4: Metabolic modeling
Scenario 5: Search for set of genes with common regulation
Problem Set 5P: Programming
Problem Set 5B: Bioinformatic tools
Scenario 6: Statistical analysis of microarray data
Problem Set 6 (part 1): Programming
Problem Set 6 (part 2): Statistical considerations
Scenario 7: Gene detection by Hidden Markov Models
Problem Set 7 (part 1): Programming
Problem Set 7 (part 2): Bioinformatic considerations and more programming
Scenario : Use of databases
Problem Set 8: Programming and bioinformatic considerations