Use Planck's constant h = 4×10-15 eV·s to calculate
The vacuum is not empty! It is filled with particle-pairs appearing and disappearing on "borrowed energy".
In a sufficiently strong electric field, a positron-electron pair will separate and gain enough energy from the field during their 6×10-22 seconds of life to pay back its debt without annihilating. The pair then become permanent citizens of the universe, created from nothing!
Many elementary particles are unstable and live only a short time. Their mass-energy cannot have a precise value and varies over a range given by the energy-time uncertainty relation. For example, a particle that lives for just 6×10-22 seconds will have a mass-energy that is uncertain by at least 1 Mev.