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Current position |
Project (Fall 1997- Spring 1998)
The role of tyrosine protein phosphorylation
in the regulation of differentiation by the cyanobacterium Anabaena
PCC 7120
Recent studies have contradicted the notion that prokaryotes lack tyrosine signal transduction schemes involving protein kinases and protein phosphatases, enzymes used in eukaryotes to regulate cell differentiation. To assess whether these enzymes are used also by the cyanobacterium Anabaena to govern differentiation, we cloned a cyanobacterial gene encoding a tyrosine so that we can regulate its expression in Anabaena. We are also analyzing different patterns of protein phosphorylation in Anabaena grown under conditions of growth or differentiation.
Presentations
Wakefield JR (1998). Role of protein phosphorylation in cell differentiation
in a prokaryote. Arts and Sciences Student Symposium. University
of Richmond.
Wakefield JR (1998). Role of protein phosphorylation in cell differentiation in a prokaryote. National Conference on Undergraduate Research. Salisbury State University.