Biol 213: Genetics (Fall 2000)*
Unit 1: Elements of Genetics
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How do cells work? Central role of protein
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Protein: Relationship between sequence
and function
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DNA: The genetic material
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Replication of DNA
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Relationship between gene and protein
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Flow of genetic information: Transcription
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The genetic code
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Translation and RNA: Who knows the code?
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Unit 2: Mendelian Genetics
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Chromosomes: Their nature & behavior
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Chromosomes: When things go wrong
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Mendelian Genetics: Simple cross and Chi-squared
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Mendelian Genetics: Dihybrid cross and probabilities
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Extensions to Mendelian genetics
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Complementation & recombination
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Linkage and mapping genetic distances
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Unit 3: Regulation of Gene
Expression and Development
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Model for transcriptional regulation:
The lac operon
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Transcriptional regulation in eukaryotes
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Why are neurons neurons and not red
blood cells?
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How transcriptional regulation controls embryogenesis
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Unit 4: Mutation and Population
Genetics
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Mutation: What kind of mutations arise?
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Mutation: How is it repaired
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Mutation: Cancer and somatic mutation
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Genome plasticity & structure
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Measuring genetic diversity & allele frequencies
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The Hardy-Weinberg equilibrium
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How can allele frequencies change in
a population?
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*Click on unit for schedule and access to class notes
and presentations