Consider how comfortable you are with the following topics (as defined by the notes Protein):

A. What amino acids are and how they differ from one another

B. How amino acids are joined to form proteins

C. How the sequence of amino acids of a protein contribute to its ultimate three-dimensional shape

D. The distinction between primary, secondary, tertiary, and quaternary structures of proteins

E. How the entire three-dimensional structure participates in forming the critical active site of chymotrypsin

F. Two ways in which hydrophobic amino acids can direct a protein to sit in a membrane

G. How a greater ability to predict protein function from its primary structure would change the world we live in

H. What all of this has to do with bioinformatics

With this in mind, how could class time best be spent to meet your needs?

Choose up to three study questions that you would most like discussed in class:

SQ7  SQ8 SQ9 SQ10 SQ11 SQ12 SQ13 SQ14

A. How far have you gotten in annotating a gene?

Consider how comfortable you are with the following topics (in the notes Annotation of a Gene):

B. If you have completed the annotation, how do you feel about it? Are you confident that your article and summary of an experiment adequately justifies the main annotation of the gene?

C. If you have not completed the annotation, what stands in your way?

D. In either case, how comfortable do you feel regarding the notion of what constitutes justification as opposed to a mere claim?