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If you encounter a question you've answered in a previous questionnaire and your answer hasn't changed, feel free to ignore the question.
Exception: Please continue to give your name, even if it hasn't changed.
I. Basic Information
A. Your name
II. Mapping and Loops
A. How far did you get in the notes concerning mapping and loops?
B. Needless to say, the notes work much better if you try each example in BioBIKE yourself. Have you done so?
C. What concerns do you have regarding mapping and loops?
D. Any issues regarding Problem Set 4?
III. Was Mendel Right?
A. How far did you get in the two tours?
B. Any issues in the biology (Part I)?
C. Any issues doing Part II on BioBIKE?
D. Any issues regarding the goals of the simulation?
E. Do you have an intuitive insight into the meaning of chi-square tests?
IV. Search for FMRP
A. How far did you get in this tour?
B. Any issues in finding the human protein or gene sequence?
C. Any issues using the sequences as queries to Blast?
D. Any issues interpreting Blast results?
E. Any idea why using the human FMRP protein as the query easily
picked up the Drosophila protein but using the human FMRP gene
failed?
F. Any favorite study questions we should consider in class?
V. Tour of Shine & Dalgarno (1975)
A. How far did you get in this tour?
B. Are you completely comfortable with the difference between transcription
and translation
-- not merely general definitions but at the level of DNA?
C. Any issues regarding the process of reading a research article like this one for a specific purpose?
D. Do you grasp the connection (in terms of specific nucleotides) between 16S rRNA sequences and the
initiation of translation?
E. Have you looked for specific sequences in real 16S rRNA (e.g. through BioBIKE)?
F. Have you looked for specific sequences upstream from the genes of phage MS2?
G. Have you looked for specific sequences upstream from the genes of E. coli?
H. Any favorite study questions we should consider in class?
VI. Miscellaneous
Any other comments, questions, suggestions, or concerns you may have?
Thanks!
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