Rationale
This course focuses on the subset of bioinformatics concerned with genome analysis. For this topic to be of more general interest than working out a crossword puzzle, it is necessary to connect the sequences of genomes to the workings of whole organisms.

Readings, Tours, and Investigations
    Notes: Strategies of Life
    Notes: Protein
    Notes: Flow of Information
    Notes: Gene Regulation and Bacteriophage
    Investigation: What is a Gene? and companion
    Investigation: Alien Genetic Code
    Reading and Tour:

Peter Lynge Madsen, Annette H Johansen, Karin Hammer, and Lone Brondsted
Journal of Bacteriology (1999) 181:7430-7438
The genetic switch regulating activity of early promoters of the temperate lactococcal bacteriophage TP901-1
Tour

Problem Set
    Problem Set 1: Intro to Molecular Biology
                            (The tour The Discovery of RNA may be helpful background for one of the questions)
    Problem Set 2: Molecular Investigations

To Hand In
    27 Jan, end of day*: Responses to questions from What is a Gene?
      3 Feb, end of day*: Problem Set 1 (whatever portion you like)
    10 Feb, end of day*: Problem Set 2

* (however you care to define it, within reason)