Rationale
This course focuses on the subset of bioinformatics concerned with genome analysis. For this topic to be of more general interest than working out a crossword puzzle, it is necessary to connect the sequences of genomes to the workings of whole organisms.

Readings, Tours, and Investigations
    Notes: Strategies of Life
    Notes: Protein
    Notes: Flow of Information
    Investigation: What is a Gene?
    Investigation: Alien Genetic Code
    Reading and Tour:

Joel G. Belasco, J.Thomas Beatty, Camellia W. Adams, Alexander von Gabain, and Stanley N. Cohen
Cell (1985) 40:171-181
Differential expression of photosynthesis genes in R. capsulata results from segmental differences in stability within the polycistronic rxcA transcript.
Tour: Part I and Part II

Problem Set
    Problem Set 1: Intro to Molecular Biology
                              (The tour The Discovery of RNA may be helpful background for one of the questions)
    Problem Set 2: Molecular Investigations

To Hand In
      5 Feb, end of day: Problem Set 1 (whatever portion you like)
    12 Feb, end of day: Problem Set 2