Rationale
This course focuses on the subset of bioinformatics concerned with genome analysis. For this topic to be of more general interest than working out a crossword puzzle, it is necessary to connect the sequences of genomes to the workings of whole organisms.
Readings, Tours, and Investigations
Notes: Strategies of Life
Notes: Protein
Notes: Flow of Information
Investigation: What is a Gene?
Investigation:
Alien Genetic Code
Reading and Tour:
On the Topology of the Genetic Fine Structure. Seymour Benzer (1959).
Proc Natl Acad Sci USA 45:1607-1620
(tour)
Line-moving program: An accessory program to the tour
Manual for the program
Problem Set
Problem Set 1: Intro to Molecular Biology
To Hand In
30 Jan, end of day: Problem Set 1 (B2, B10, C4, C6, D4)