Pscan DAS Department Miklos

"DAS" - Transmembrane Prediction server


Computation is in progress. It takes a minute or two typically.
. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . Done
Your query is:
MEAIIMTTLPNLTTDAGDSSFWLTGALSLSEMLANSSHSHSTGSTTSTAG
SSATESSAVNVGKDHDKHVNDSVSTGLSNYSNYPSYIHYRDKYDLSYIAK
VNPFWLQFEPPKSSTFLIMAALYCLISVVGCVGNAFVIFMFANRKSLRTP
ANILVMNLAICDFLMLIKCPIAIYNNIKEGPALGDIACRLYGFVGGLSGT
CAIGTLTAIALDRYNVVVHPLQPLRRCSRLRSYLIILLIWCYSFLFAVMP
ALDIGLSVYVPEGFLTTCSFDYLNKEMPARIFMALFFVAAYCIPLTSIVY
SYFYILKVVFTASRIQSNKDKAKTEQKLAFIVAAIIGLWFLAWSPYAIVA
MMGVFGLERHITPLGSMIPALFCKTAACVDPYLYAATHPRFRVEVRMLFY
GRGVLRRVSTTRSSYMTRSRSSFTHRLRTSTTGEGGMGDHRMENYLMNNN
LMMVPEETEENEEIVVVAEINNSISSVMEQSKF

Potential transmembrane segments Start Stop Length ~ Cutoff 116 140 25 ~ 1.7 117 139 23 ~ 2.2 153 170 18 ~ 1.7 155 167 13 ~ 2.2 190 210 21 ~ 1.7 232 258 27 ~ 1.7 233 252 20 ~ 2.2 281 310 30 ~ 1.7 282 309 28 ~ 2.2 329 355 27 ~ 1.7 330 343 14 ~ 2.2 347 353 7 ~ 2.2 367 372 6 ~ 1.7
The DAS curve for your query:

The DAS curve of the query is also available in PostScript format.

You may wish to compare your curve with those obtained for the test set. It gives you an idea about the confidence of the prediction.


"DAS" curves of the test set
These curves are obtained by pairwise comparison of the proteins in the test set in "each against the rest" fashion. There are two cutoffs indicated on the plots: a "strict" one at 2.2 DAS score, and a "loose" one at 1.7. The hit at 2.2 is informative in terms of the number of matching segments, while a hit at 1.7 gives the actual location of the transmembrane segment. The segments reported in the "FT" records of the SwissProt database are marked at 1.0 DAS score ("FT lines").
ALKB_PSEOL, ATPL_ECOLI, COX2_PARDE, COX3_PARDE, CX1B_PARDE, CYDA_ECOLI, CYDB_ECOLI, CYOA_ECOLI, CYOB_ECOLI, CYOC_ECOLI, CYOD_ECOLI, CYOE_ECOLI, DHG_ECOLI, DMSC_ECOLI, DSBB_ECOLI, ENVZ_ECOLI, EXBB_ECOLI, EXBD_ECOLI, FTSH_ECOLI, FTSL_ECOLI, FUCP_ECOLI, GLPT_ECOLI, HISM_SALTY, HISQ_SALTY, HOXN_ALCEU, IMMA_CITFR, KDPD_ECOLI, KGTP_ECOLI, LACY_ECOLI, LSPA_ECOLI, MALG_ECOLI, MELB_ECOLI, MOTA_ECOLI, MOTB_ECOLI, MTR_ECOLI, OPPB_SALTY, OPPC_SALTY, PHOR_ECOLI, RHAT_ECOLI, SECD_ECOLI, SECE_ECOLI, SECY_ECOLI, TOLQ_ECOLI, TOLR_ECOLI