My advice on the matters for the day (as listed in the calendar):

• Crick (1961) et al and its companion: This article is not easy to read and more than most requires you to have a good grasp of the underlying experiment. I suggest that you devote most of your efforts to the first three pages of the companion and the first page of the article, focusing on the experimental system. You will almost certainly want to avail yourself of the resources described to help you in this task (see the Related Articles section). The Crick Scientific American article can provide a more complete introduction to the experiment. The first couple of pages of the Benzer Scientific American article can provide insight as to how the T4 phage system works.
   
• Simulations of Crick (1961) et al: If you like you can get a head start on this (on the Oct 15 calendar). The simulation may help you understand how the experiment works, saving you grief as you read the article. There will be more time devoted to this next week.
   
• Problem Set 5: Do Problems #1 and #2 outside of class. They should either take almost no time, or you'll find them nearly impossible. In the latter case,bring questions to help you move forward. We will probably use class time for problems #3.