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My advice on the matters for the day (as listed in the calendar):
- Jones & Nirenberg (1962): Use the companion, to guide your introduction to this article. There's only one kind of experiment, one that might seem foreign at first but is not too challenging once you grasp what is happening. You might look ahead to recreating the experiment yourself, with the aid of the
Alien Genetic Code simulation, but we'll go over that on Thursday.
- Problem Set 5: Do or at least begin Problems #1 and #2 outside of class. They should either take almost no time, or you'll find them nearly impossible. In the latter case, bring questions to help you move forward in understanding the basic concepts underlying these questions. Otherwise we will focus on class time on problems #4 and #5. Take a look at them to see what issues you may have (but no need to go deeply into the problems).
- Research Proposal: I'll take you through the Proposal Description and Website Map
I. Basic Information
A. Your name
II. Old business
- Crick (1958) and the coding problem
Any parting thoughts on the companion to Crick (1958)?
- Research proposal?
Progress? Problems?
III. Jones & Nirenberg (1962) Survey of RNA codewords
A. How far have you gotten in Jones & Nirenberg (1962) (and its
companion)?
B. Consider how comfortable you are with the following topics regarding these matters:
- The overall goal of the work by Nirenberg and others
- The specific focus of Jones & Nirenberg (1961)
- The nature of the experiment
- The nature of RNA produced by polynucleotide phosphorylase
- Theoretical expectations of experiment J108, Table 3
- Interpretation of Table 3
- How in principle to deduce the alien genetic code
- How to use Alien Genetic Code within BioBIKE
IV. Miscellaneous
Any other comments, questions, suggestions, or concerns you may have?
(nb. Issues concerning your proposal are always welcome)
Thanks!
REMEMBER TO CLICK SUBMIT!
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