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My advice on the matters for the day (as listed in the calendar):
Protein
- Protein (notes): If you haven't looked through these notes, now is the time. We'll be moving on.
- Sanger and Tuppy (1951): Main topic for today, the first three sections of the companion to the article -- understanding the experimental procedure.
- Paper chromatography (tutorial): A direct assault on the experimental procedure. Possibly your best shot at understanding the experiment. I suggest you go through it before class and offer questions, if you have any.
- What is a Gene?: Last chance to work on this in class. You might want to go as far as you can before class, so that if you encounter a problem, we can solve it.
- Problem Set 2: Protein: We will spend time on any question(s) you like. Default is Problem Set 2 #2 and #3.
Research Proposal:
- Progress reports: By this time you will have identified candidate mentors. Be prepared to give an overview of your candidates, what research problems each faculty candidate addresses and the types of experiments they do. Be prepared also to justify why you think the experiments relate to molecular biology (how does something work at the molecular level).
I. Basic Information
- Your name
II. Old business
(no need to repeat anything you've said in a previous questionnaire)
- Protein
Anything further you'd like to discuss regarding the notes entitled
Protein?
- What is a Gene?
Any obstacles that have come up in your progress through What is a Gene?
- Research Proposal
Are you relatively clear on the nature of the research proposal and how it will play out? (if not, try the
Research Proposal page)
Are you happy with progress in identifying a mentor?
Was discussing mentors within your group helpful? If so, how?
- Observation vs Conclusion
The meanings of these words I'm pushing on you are quite a bit different from the popular meanings, and so it takes time to see the distinction. Progress?
Do you see why the proposed meanings put you in a better position to consider scientific findings? (perhaps other findings as well?)
Did the exercise looking at Winter et al (1987) help? If so, how? If not, what do you think you need?
III. Sanger & Tuppy (1951)
- Have you found and downloaded the article Sanger & Tuppy (1951) cited in the
companion?
Are you sure you got the right one? How do you know?
- How far have you gotten in a productive reading of the article (not just the companion)?
You can answer by referring to the last section you read or the last study question you addressed (e.g. SQ12) in the companion.
- Consider how comfortable you are with the following topics (as defined by the companion to Sanger and Tuppy):
- The distinction between a research article and a review article? Between a research article and a science news article?
- The overall strategy Sanger & Tuppy used to determine the sequence of insulin
- What paper chromatography is and how it works (did the
presentation on paper chromatography help you?)
- Study questions 1 through 9
With this in mind, how could class time best be spent to meet your needs?
As always, refer to specific matters and relate your current understanding and efforts you've made to address your discomfort.
Do you have any other questions concerning the material in the notes?
IV. Miscellaneous
A. Are group problem sessions in class useful to you? Can you think of any way in which they could be more useful?
B. Any other comments, questions, suggestions, or concerns you may have?
Thanks!
REMEMBER TO CLICK SUBMIT!
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