BNFO 300 
Molecular Biology Through Discovery
Questionnaire on: Gene Regulation and Bacteriophage
(please press SUBMIT button when finished)
Fall 2017  


I. Basic Information

A. Your name  
II. Old business
  1. Brenner et al (1961) - the rationale and the experiment
    Regarding Brenner et al (1961) and its companion, do you understand the three hypotheses they were trying to test? Do you understand the nature of the experiment(s) they performed?

     
  2. Problem Set 7
    Any concerns about Problem Set 7, question 3 (redrawing figures from Brenner et al (1961))?

     
  3. Research proposal?
    Are you on track with a summary that tells a full story about a key published experiment?
    Do you have an idea on how to go about preparing an outline of your developing research proposal?
    Any other issues concerning your proposal?

III. Gene regulation

A. How far have you gotten in the notes entitled Gene Regulation and Bacteriophage?
     

B. Consider how comfortable you are with the following and comment below as to how class might be most useful to you:

  • Do you understand the different levels of gene regulation?
  • Do you understand the relationship between transcriptional proteins (like RNA polymerase and repressors) and specific DNA sequences (like promoters and operators)?
  • Do you recognize common features of the sequences of actual promoters and operators in the cI-cro region of lambda?
  • Do you understand the power of regulatory feedback loops?
  • Do you understand how the interplay between the lambda repressor and Cro protein might achieve a stable decision of lysogeny vs lysis?
  • Any other regulation-related issues?
     
IV. Miscellaneous
Any other comments, questions, suggestions, or concerns you may have?

Thanks!

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