BNFO 300 
Molecular Biology Through Discovery
Research Proposals (as of 20 Nov 2017)
Fall 2017 

Listed below are proposals to be presented May 2017. Each proposal is to justify and describe a single experiment aimed at addressing a small part of a large and significan question. The aim is depth, getting to the bottom of an experiment to the extent that the presenter can explain the principles behind all techniques used and how the techniques contribute to the experiment. Each proposer has been mentored by a member of the VCU research community.

You can see general advice that was given regarding how to write a research proposal and how to give a presentation. Each presentation will be about 8 minutes. If you like, you can see what has been done in previous years by going to VCU Review Panel on Molecular Biology Research for the years 2012, 2013, 2014, 2016, and Fall 2017 (there was no 2015).

PROPOSER MENTORTITLE
Shradda AdhikariEun LeePremature fetal termination and its association with ERAP2(N)
Elaf AlaithanGlen KelloggEvaluating and comparing various human sphingosine kinase inhibitors
Ashley AroraEun LeeImmune response when ERAP2-N is introduced to Melanoma cell line MRN-1
Ashria AroraJoyce LloydMeasurement of fetal gamma-globin expression due to KLF1 being a negative or positive regulator
Sharoon ArshadRebecca MartinFurin deletion in B cells alters ADAM10 prodomain processing and the downstream effects on allergic asthma
Ayshah AsmatLuni EmdadAEG-1 alters methylation status of IGFBP7 promoter via activation of the Wnt/?-catenin signaling pathway in HCC
Amanda AtrashJavier Gonzalez-MaesoDisruption of NDEL1 via knockout of DISC1 stunts dendritic spine structure in the hippocampus region of mice
Oluchi ChigbuJill BettingerDo higher levels of EPA in C. elegans affect NPR-1 regulation of AFT?
Rebecca CulpepperRita ShiangDiscovery of possible connection between cln3 gene and cisd2 gene through notch signaling
Samhitha DhandamudyGregorio GilExamining the role of diacylglycerol in the protein kinase C pathway in lipid-induced insulin resistance
Josh FungSarah RothschildDetermining if the transcription factor, Tbx5, is necessary within zebrafish myocardial regeneration
Shahzeb HasanHamid AkbaraliThe role of G-alpha-s and G-beta-gamma in adenylyl cyclase super activation following chronic opioid exposure
Shwetha KochiPat TrimmerInhibition of prion-like properties in alpha-synuclein using promazine derivatives
Angela MichalakMaria RiveraHow does CagA in H. pylori contribute to apoptosis in gastric cancer cells?
Sam PortilloGlen KelloggComparison of phenylalanine v. tyrosine rotamers with respect to alpha helix structure using 3D modeling software
Aarthi PrakashJitender MehlaMapping the Protein-Protein Interactions of LapA in LPS Assembly
Akhil RamaswamyAndrew Van der Vaart5-HT1B-receptor regulation by p-GSK3B due to acute ethanol exposure on mice
Cove SoyarsJitender MehlaRole of hydrophobicity in Ser-83 amino acid substitutions of DNA gyrase subunit A encoding gyrA
Mouni TalariBinks WattenbergThe upregulation of CerS3 to increase production of ultra-long chain (ULC) ceramides in psoriatic epidermal keratinocytes of mice
Katie VishwanathJared ProsserMeasurement of protein aggregation levels in mutant scs2 gene of yeast to determine whether the ubiquitination proteasome system of the unfolded protein response can be inhibited
Mailat YonasMadhu GowdaIs p53 more likely to trigger apoptosis or cellular senescence as a response to a tumor or DNA damage?
Samuel YoungJeff ElhaiNostoc punctiforme mutate of hormogonia reacts with pilius begin removed