BNFO 300 
Molecular Biology Through Discovery
Questionnaire on: Brenner et al (1961) - The discovery of mRNA (continued)
(please press SUBMIT button when finished)
Fall 2014  


I. Basic Information

A. Your name 
II. Old business
(no need to repeat anything you've said in a previous questionnaire)
  1. Research proposal?
    Progress? Problems? Progress on summary?
    Have you looked ahead to the proposal outline (target date Nov 14)? Approaching readiness?

III. Brenner et al (1961)
(no need to repeat anything you've said in a previous questionnaire)

A. Have you gotten the full text of the article? If so, how far have you gotten in it (and its companion)?
     

B. Consider how comfortable you are with the following topics regarding these matters:

  • The general outline of Pardee, Jacob, and Monod's experiment
     
  • The implications of linear vs exponential production of enzyme in that experiment
     
  • The general outline of Riley and Pardee's experiment and its implications
     
  • The three models considered by Brenner et al
     
  • Density shift experiments and density gradient centrifugation
     
  • Interpretation of Figures 2 - 8 in Brenner et al
     
  • Pulse-chase experiments
     
         

C. Choose up to five study questions that you would most like discussed in class and explain why.
     

IV. Miscellaneous

Any other comments, questions, suggestions, or concerns you may have?

Thanks!

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