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I. Basic Information
A. Your name
II. Old business
(no need to repeat anything you've said in a previous questionnaire)
- Summary of an experiment described in a research article
Clear on the
why,
what, and
how, of writing a summary? And
how to critique someone else's?
Crick et al (1961) and the triplet code
Regarding the companion to Crick (1961), any concerns about mutagenesis by acridines? Recombination between two phages? The nature of suppressor mutations? How to construct multiply mutant phages? What the double and triple mutants say about the genetic code?
Jones & Nirenberg (1962) and in vitro translation
Regarding the companion to Jones & Nirenberg (1962), any concerns about how the experiment works? The nature of RNA produced by polynucleotide phosphorylase? Interpretation of Table 3? Quantitative expectations from our own perspective? How do deduce an alien genetic code?
Research proposal?
Progress? Problems?
III. Belozersky & Spirin (1957)
A. How far have you gotten in this article (and its companion)?)?
B. Consider how comfortable you are with the following topics regarding these matters:
- The one-gene - one-ribosome - one-protein model (Fig. 2 of the companion)
- Volkin and Astrachan's result
- How to read the table of Belozersky & Spirin
- How to calculate (G+T) / (A+C) etc
- The relationship of Belozersky & Spirin's results to the 1-gene 1-ribosome 1-protein model
C. Choose up to five study questions that you would most like discussed in class and explain why.
IV. Miscellaneous
Any other comments, questions, suggestions, or concerns you may have?
Thanks!
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