BNFO 300 
Molecular Biology Through Discovery
Questionnaire on: Perutz et al (1965)
(please press SUBMIT button when finished)
Fall 2014  


I. Basic Information

A. Your name 
II. Old business (no need to repeat anything you've said in a previous questionnaire)
  1. Sanger & Tuppy (1951)
    Any parting thoughts on Sanger & Tuppy (1951), the companion, paper chromatography, Problem Set 4, Problem 1, or related issues?

    This is the first time I tried dividing Problem Set 4, Problem 1 by amino acid. Of course the purpose was to give each person a particular area of expertise in the hope of increasing meaningful interactions. Do you think this was helpful? How could it have been more helpful?

III. Problem Set 4 (Protein Structure)
  1. Have you taken a look at any of the problems in this problem set beyond Problem 1, particularly Problems 6 and 7?
     
  2. Do you any issues or concerns come to mind?
IV. Perutz et al (1965)
  1. Have you found and downloaded the article Perutz et al (1965) cited in the companion?  
     
  2. How far have you gotten in the companion to that article? Refer, perhaps, to the last study question you addressed (e.g. SQ12).  
     
  3. How far have you gotten in Hemoglobin Structure? Refer, perhaps, to the last section and view you completed (e.g. 4, View 7).  
    (If you are not able to get the tutorial to run, here's a possible solution)
     
    Consider how comfortable you are with the following topics (as defined by the companion to Perutz et al):
     
  4. The different ways protein structures are presented graphically
     
  5. The basis for the formation of alpha helices
     
  6. The role of hydrophobicity in determining the three dimensional structure of proteins
     
  7. How to use Protein Explorer, given help
     
  8. The significance of invariant amino acids in the structure of globin
     
  9. The significance of prolines in the structure of globin
     
  10. With this in mind, how could class time best be spent to meet your needs?

Choose up to five study questions, those that you have already struggled with, that you would most like discussed in class:

SQ1  SQ2 SQ3 SQ4 SQ5 SQ6 SQ7  SQ8  SQ9 
SQ10 SQ11 SQ12 SQ13 SQ14 SQ15 SQ16 SQ17 
SQ18 SQ19  SQ20 SQ21 SQ22 SQ23 SQ24 SQ25 
SQ26 SQ27 SQ28 SQ29 SQ30 SQ31 SQ32 SQ33 
V. Miscellaneous

Any other comments, questions, suggestions, or concerns you may have?

Thanks!

REMEMBER TO CLICK SUBMIT!