BNFO 300 
Molecular Biology Through Discovery
Questionnaire on notes: Brenner et al (1961) - Demonstration of unstable RNA
(please press SUBMIT button when finished)
Fall 2013 


I. Basic Information

A. Your name 
II. Old business -- Crick et al (1961) General Nature of the Genetic Code

Any final concerns about Crick et al (1961) and related matters?
     

III. Old business -- Jones & Nirenberg (1962) Survey of RNA codewords

Any final concerns about Jones & Nirenberg (1962) and related matters?
     

IV. Old business -- Belozersky & Spirin (1957)

A. How far have you gotten in this article (and its companion)?
     

Consider how comfortable you are with the following topics regarding these matters:

B. The one-gene - one-ribosome - one-protein model (Fig. 2 of the companion)

C. Volkin and Astrachan's result

D. How to read the table of Belozersky & Spirin

E. How to calculate (G+T) / (A+C) etc

F. The relationship of Belozersky & Spirin's results to the 1-gene 1-ribosome 1-protein model
     

Choose up to three questions that you would most like discussed in class:

SQ1  SQ2 SQ3 SQ4 SQ5 SQ6 SQ7  Scenario 1  Scenario 2 
V. Brenner et al (1961)

A. How far have you gotten in this article (and its companion)?
     

Consider how comfortable you are with the following topics regarding these matters:

B. The general outline of Pardee, Jacob, and Monod's experiment

C. The implications of linear vs exponential production of enzyme in that experiment

D. The general outline of Riley and Pardee's experiment and its implications

E. The three models considered by Brenner et al

F. Density shift experiments and density gradient centrifugation

G. Interpretation of Figures 2 - 8 in Brenner et al

H. Pulse-chase experiments
     

Choose up to six questions that you would most like discussed in class:

SQ1  SQ2 SQ3 SQ4 SQ5 SQ6 SQ7  SQ8  SQ9 
SQ10 SQ11 SQ12 SQ13  SQ14 SQ15 SQ16 SQ17 
SQ18  SQ19 SQ20 SQ21 SQ22 SQ23 SQ24 SQ25 
SQ26 SQ27 SQ28 SQ29 SQ30 SQ31  SQ32 SQ33 
SQ34 SQ35 SQ36 SQ37  SQ38  SQ39  SQ40 SQ41 
SQ42 SQ43  SQ44 SQ45 SQ46 SQ47 SQ48 
VI. Miscellaneous

Any other comments, questions, suggestions, or concerns you may have?

Thanks!

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