Biol 591

Introduction to Bioinformatics Course at a Glance : List of topics

Fall 2003

 

	Scientific Problem	Bioinformatic Tool
1	Comparison of genomes of pathogenic and nonpathogenic bacteria, looking for genes responsible for pathogenesis	Parsing programs
2	Identification of a possible regulatory site in genomic DNA	Simple simulations, Pattern search programs
3	Alignment of mystery sequence with known anthrax toxins	Sequence alignment
4	Analysis of a biochemical pathway in order to determine the best site to target a drug	Metabolic modeling
5	Search for set of genes with common regulation	Position-specific probability matrices
6	Distinguishing different types of leukemia in order to target treatment	Statistical analysis of microarray data
7	Prediction of structure of protein of industrial importance	Molecular threading
8	Identification of genes of foreign origin	Markov models