Introduction to Bioinformatics (Fall 2003)
Questionnaire on notes: Biological Information and Protein Structure and Function
(please press SUBMIT button when finished)

I. Basic Information

A. Your name 

B. What do you need? This has been a weird semester, because of circumstances that compelled me to be away the first four days. By this time I ordinarily would have a feel of who everyone is and where they stand. I certainly don't. Could you help me out by giving me a summary of where you stand regarding what has happened thus far in the semester and what you feel you need to make this a useful experience for you?

II. Biological Information
A. Do you understand how information passes from DNA through RNA to protein? (at the level set in the reading) 

B. Can imagine a biological system that displays a degree of complexity suggested in the reading? 

C. Do you see (at the level set in the reading) how genes might determine the function of an organism? 

D. Do you understand how amphipathic lipids can self-assemble into the sphere shown in Fig. 3B? 

E. Do you understand the relationship between monomers and the four major types of biological polymers? 

F. Do you see in general how enzymes might determine the nature of a cell? 

G. Choose up to two study questions that you would most like discussed in class:

SQ1 SQ2 SQ3 SQ4 SQ5 SQ6
Comments for questions II.A through II.F:
III. Protein structure and function
A. Do you understand what an amino acid is and how they differ from one another? 

B. Do you understand how amino acids are joined to form proteins? 

C. Do you understand in general how the sequence of amino acids of a protein contribute to its ultimate three-dimensional shape? 

D. Do you understand the distinction between primary, secondary, tertiary, and quaternary structures of proteins? 

E. Do you understand how the entire three-dimensional structure participates in forming the critical active site of chymotrypsin? 

F. Do you understand two ways in which hydrophobic amino acids can direct a protein to sit in a membrane? 

G. Do you see how a greater ability to predict protein function from its primary structure would change the world we live in? 

H. Do you see what all of this has to do with bioinformatics? 

I. Choose up to three study questions that you would most like discussed in class:

SQ8 SQ9 SQ10 SQ11 SQ12 SQ13 SQ14
Comments for questions III.A through III.H:
IV. Put here any miscellaneous comments, questions, suggestions, concerns you may have
 

Thanks!

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